Acute platelet deposition after carotid endarterectomy in sheep: Vein patch compared with gelatin-sealed Dacron and polytetrafluoroethylene patch closure

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Presentation transcript:

Acute platelet deposition after carotid endarterectomy in sheep: Vein patch compared with gelatin-sealed Dacron and polytetrafluoroethylene patch closure Anatoly I. Margovsky, MD, Alan C. Meek, MD, Reginald S.A. Lord, MD Journal of Vascular Surgery Volume 24, Issue 2, Pages 200-206 (August 1996) DOI: 10.1016/S0741-5214(96)70094-0 Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Carotid patch angioplasty with 6 mm (A) and 12 mm (B) width e-PTFE patch material. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Carotid patch angioplasty with 6 mm (A) and 12 mm (B) width e-PTFE patch material. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Excised 12 mm patch width arterial segments with 1-hour thrombosis deposition on (A) PTFE patch surface and adjacent arterial wall; (B) Dacron patch surface and adjacent arterial wall at 1 hour after patch implantation. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Excised 12 mm patch width arterial segments with 1-hour thrombosis deposition on (A) PTFE patch surface and adjacent arterial wall; (B) Dacron patch surface and adjacent arterial wall at 1 hour after patch implantation. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Acute 111-In-labeled platelet uptake on 6 mm and 12 mm width patches. Log scale shows difference in platelet activity between patch width and patch materials. Numbers represent mean data for each angioplasty group. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Acute 111-In-labeled platelet uptake on arterial wall opposite to 6 mm and 12 mm width patches. Log scale shows difference in platelet accumulation on arterial wall with respect to each angioplasty group. Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Scanning electron microscopy appearance of carotid artery after simulated endarterectomy; disrupted endothelial surface covered by platelets and fibrils (original magnification ×800). Journal of Vascular Surgery 1996 24, 200-206DOI: (10.1016/S0741-5214(96)70094-0) Copyright © 1996 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions