Torsades de pointes with pseudo–T wave alternans during rociletinib therapy: A novel manifestation of a rare side effect Alexandra E. Teng, MD, Michael.

Slides:

Advertisements

Similar presentations

A novel de novo calmodulin mutation in a 6-year-old boy who experienced an aborted cardiac arrest Kazuhiro Takahashi, MD, PhD, Taisuke Ishikawa, DVM,

Advertisements

Sudden Cardiac Death, Mitral Valve Prolapse, and Long QT Syndrome

Premature ventricular contraction–induced polymorphic ventricular tachycardia after leadless pacemaker implantation: A unique adverse effect of leadless.

Atrioventricular hysteresis pacemaker mode promoting a short-long-short sequence at the onset of ventricular tachycardia Neiberg de Alcantara Lima, MD,

Erroneous shock by an AED: Importance of obtaining AED tracing to prevent inappropriate ICD implantation Brian J. Cross, MD, Mark S. Link, MD, FHRS

Ablation of ventricular tachycardia from the aortic root after transcatheter aortic valve replacement Uma N. Srivatsa, MBBS, MAS, FHRS, Eric J. Nordsieck,

A novel de novo calmodulin mutation in a 6-year-old boy who experienced an aborted cardiac arrest Kazuhiro Takahashi, MD, PhD, Taisuke Ishikawa, DVM,

Swimming pool saline chlorination units and implantable cardiac devices: A source for potentially fatal electromagnetic interference John Wight, BS,

Iatrogenic atrial septal defect with right-to-left shunt following atrial fibrillation ablation in a patient with arrhythmogenic right ventricular cardiomyopathy

A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone Alexandra Marx, MD, Björn Lange, MD, Carsten.

A case of paroxysmal atrioventricular block–induced cardiac arrest

Paradoxical reflex bradycardia after epinephrine infusion for arrhythmia induction in the electrophysiology laboratory Timothy R. Larsen, DO, Karoly.

Left ventricle penetration—A rare complication of transseptal puncture and catheter ablation for supraventricular tachycardia Nelson Chavarria, MD, Seth.

Spectrum of cardiac manifestations from aconitine poisoning

Prakash G. Suryanarayana, MD, David S. Frankel, MD, FHRS, Francis E

Is it bradycardia or something else causing symptoms?

Quinidine effective for the management of ventricular and atrial arrhythmias associated with Brugada syndrome Laura Halperin, BSc, Greg Mellor, MD, Mario.

Novel CALM3 mutations in pediatric long QT syndrome patients support a CALM3- specific calmodulinopathy Marie-A. Chaix, MD, MSc, Tamara T. Koopmann, PhD,

Ruchit Shah, MD, Vineet Kumar, MD, FHRS HeartRhythm Case Reports

Use of topical lidocaine in eliminating mechanically stimulated ventricular fibrillation in a patient with short QT syndrome Maria J. Farag, BS, Joseph.

HeartRhythm Case Reports

Respiratory rate trending as a cause for atrial lead noise: A first report in an implantable cardioverter-defibrillator patient Isla McClelland, MD,

Santiago O. Valdés, MD, Andrew P. Landstrom, MD, PhD, Andrew E

Maged F. Nageh, MD,FHRS, Kamal Kotak, MD HeartRhythm Case Reports

Recurrent idiopathic polymorphic ventricular tachycardia/ventricular fibrillation successfully treated by cardiac sympathetic denervation Faisal Matto,

Increased threshold in nonselective His-bundle pacing suspected to be caused by amiodarone JoonHyuk Kim, MD, Seth Goldbarg, MD, FHRS, Steven Leung, MD,

Use of intravenous sotalol in newborns with supraventricular tachycardia Hannah Kim, MD, Jennifer Wolff, PharmD, BCPPS, Aarti Dalal, DO, George F. Van.

Atrial pacing for the management of ventricular arrhythmias in Andersen-Tawil syndrome Opeyemi Fadahunsi, MBBS, MPH, Bilal Shaikh, DO, Andrew Rettew,

Atrioventricular block and pause-dependent torsade de pointes

Jonathan T. Jaffe, MD, Lee-Gardie Jean, MD, Richard J. Murray, MD

Surgical correction of tricuspid regurgitation in patients with ARVD/C

Left axillary active can positioning markedly reduces defibrillation threshold of a transvenous defibrillator failing to defibrillate at maximum output

Recurrent premature ventricular contraction–induced ventricular fibrillation and resuscitated sudden death in a 26-year-old pregnant woman with bileaflet.

Very late occurrence of complete heart block without preexisting atrioventricular conduction abnormalities: A rare complication after transaortic valvular.

Termination of anticoagulation therapy at 45 days after concomitant atrial fibrillation catheter ablation and left atrial appendage occlusion resulting.

Complete congenital heart block: A case of multilevel block

Srinath C. Yeshwant, MD, Mitchell H. Tsai, MD, MMM, Bradley R

Keith Suarez, MD, Ryan Mack, MD, Evan L

Emilio L. Garcia, MD, Robert Kim, MD, Steve S. Hsu, MD, FHRS, John N

A novel GJA1 mutation causing familial oculodentodigital dysplasia with dilated cardiomyopathy and arrhythmia Carol A. Wittlieb-Weber, MD, Katrina M.

Paroxysmal 1:1 narrow complex tachycardia: What is the mechanism?

Expanding the electrical phenotype of NKX2-5 mutations: Ventricular tachycardia, atrial fibrillation, and complete heart block within one family Simone.

Intravenous sotalol for conversion of atrial flutter in infants

QRS normalization during atrial pacing in a patient with complete left bundle branch block: What is your diagnosis? Oholi Tovia-Brodie, MD, Yoav Michowitz,

Polymorphic ventricular arrhythmia triggered by temporary epicardial right ventricular stimulation after cardiac surgery Carlos Lopez, MD, Teresa Oloriz,

Simrit K. Warring, MS, Heather N. Anderson, MD, J

Santosh K. Padala, MD, Kenneth A. Ellenbogen, MD, FHRS, Jayanthi N

Vagally mediated ventricular arrhythmia in Brugada syndrome

A case of Takotsubo cardiomyopathy showing two modes of initiation for ventricular fibrillation: Augmented J-wave and torsade de pointes with QT prolongation

Mitral valve repair results in suppression of ventricular arrhythmias and normalization of repolarization abnormalities in mitral valve prolapse Wael.

Complexity of ranolazine and phenytoin use in an infant with long QT syndrome type 3 Reina Bianca Tan, MD, Sujata Chakravarti, MD, Melissa Busovsky-McNeal,

Long-term follow-up of permanent atrial standstill in a German family with mutation in the SCN5A gene H. Immo Lehmann, MD, Ulf Meltendorf, MD, Helmut.

Benjamin A. Blais, MD, Gary Satou, MD, Mark S

An unusual cause of HV prolongation

Justin D. Smith, MD, Jeffrey M. Vinocur, MD HeartRhythm Case Reports

Subcutaneous implantable cardioverter-defibrillator implantation in a patient with bilateral pectoral deep brain stimulators Thor Tejada, MD, Faisal.

Different rate-dependent responses between J waves and the notches on an epicardial local electrogram in a patient with idiopathic ventricular fibrillation

Familial long QT syndrome and late development of dilated cardiomyopathy in a child with a KCNQ1 mutation: A case report Kiona Y. Allen, MD, Victoria.

Dexamethasone suppresses long QT phenotype in patient with acute promyelocytic leukemia treated with arsenic Jeffrey R. Winterfield, MD, FHRS, David.

Intermittent failure to capture: What is the mechanism?

Unusual severe hemodynamic failure associated with standard dose of intravenous flecainide for pharmacological cardioversion of atrial fibrillation Aref.

Raja Zaghlol, MD, Rama Hritani, MD, Susan O’Donoghue, MD

Early repolarization syndrome: A case report focusing on dynamic electrocardiographic changes before ventricular arrhythmias and genetic analysis Vern.

Jeffrey Y. Lin, MD, Petar Igic, MD, FHRS, Kurt S

Cardiac implantable electronic device malfunction after deceleration injury without obvious chest trauma Amr F. Barakat, MD, Brian Cross, MD, Jonathan.

Use of topical lidocaine in eliminating mechanically stimulated ventricular fibrillation in a patient with short QT syndrome Maria J. Farag, BS, Joseph.

Resolution of new left bundle branch block and ventricular tachycardia with immunosuppressive therapy in a patient with cardiac sarcoidosis Aatish Garg,

Prolonged QT Syndrome: Perioperative Management

Bradycardia-induced polymorphic ventricular tachycardia after radiofrequency catheter ablation for right atrial flutter Matthew Zada, BMedSc(Hons), MBBS,

HeartRhythm Case Reports

Presentation transcript:

Torsades de pointes with pseudo–T wave alternans during rociletinib therapy: A novel manifestation of a rare side effect Alexandra E. Teng, MD, Michael Share, MD, Jeffrey J. Hsu, MD, Sarah R. Rettinger, MD, Edward Garon, MD, Jonathan Goldman, MD, Eric H. Yang, MD, Roderick Tung, MD, FHRS HeartRhythm Case Reports Volume 4, Issue 10, Pages 490-493 (October 2018) DOI: 10.1016/j.hrcr.2018.07.011 Copyright © 2018 Heart Rhythm Society Terms and Conditions

Figure 1 Twelve-lead electrocardiogram at presentation demonstrating macroscopic T-wave changes, with most pronounced abnormalities after premature atrial contraction–induced pauses. Corrected QT interval by the Bazett formula is 582 ms. Asterisks indicate premature atrial contractions and arrows indicate T-wave changes. HeartRhythm Case Reports 2018 4, 490-493DOI: (10.1016/j.hrcr.2018.07.011) Copyright © 2018 Heart Rhythm Society Terms and Conditions

Figure 2 Premature ventricular contractions with R-on-T phenomenon during deeply inverted T-wave prolongation and initiation of torsades de pointes. HeartRhythm Case Reports 2018 4, 490-493DOI: (10.1016/j.hrcr.2018.07.011) Copyright © 2018 Heart Rhythm Society Terms and Conditions

Figure 3 Gradual improvement in corrected QT interval prolongation and macroscopic T-wave changes on hospital days 2 through 5. HeartRhythm Case Reports 2018 4, 490-493DOI: (10.1016/j.hrcr.2018.07.011) Copyright © 2018 Heart Rhythm Society Terms and Conditions