2013 Annual Report - 36th Edition DEATHS CHAPTER 3 ANZDATA Registry Annual Report 2013 Philip Clayton CHAPTER 9 KIDNEY DONATION 2013 Annual Report - 36th Edition

Survival among People who Commenced Figure 3.1 Survival among People who Commenced Dialysis 2003 - 2012 (Non-Indigenous) % (95% CI) Age at Start Time Point (Number of Years from dialysis start) Proportion Surviving Aust (95 % CI) Proportion Surviving NZ (95 % CI) 0– 24 1 97 (95-98) 96 (90-99)   2 93 (90-95) 93 (85-97) 5 90 (86-93) 83 (64-92) 25—44 97 (96-98) 98 (96-99) 92 (90-93) 93 (89-96) 80 (78-83) 74 (65-81) 45—64 92 (91-92) 91 (89-92) 85 (84-85) 81 (78-84) 61 (59-62) 54 (49-58) 65—74 86 (85-87) 85 (82-87) 74 (72-75) 72 (69-76) 42 (41-44) 34 (30-39) 75—84 80 (79-81) 77 (72-81) 64 (63-66) 56 (51-61) 28 (26-29) 19 (15-24) 85 + 70 (66-74) 67 (46-80) 51 (47-56) 45 (28-61) 20 (15-24) 17 (5-34) ANZDATA Registry Annual Report 2013

(per 100 patient years, 95% CI) Figure 3.2 Death Rates During Renal Replacement Therapy All Patients Included who Received Treatment During 2012 Group Dialysis Mortality Rate (per 100 patient years, 95% CI) Transplant Overall Rate Confidence Intervals Confidence Intervals Per 100 patient years Lower Upper Australia 12.7 12.2 13.4 1.8 1.6 2.1 New Zealand 14.6 13.2 16.2 1.9 1.3 2.8 Ages (Years)   < 25 3.7 2.0 7.0 0.4 0.1 1.5 25—44 4.9 3.9 6.1 0.5 0.3 0.8 45—64 9.3 8.5 10.2 1.4 1.1 65—84 17.1 16.1 18.2 5.1 4.1 6.2 ≥ 85 36.5 31.6 42.1 5.4 8.6 Diabetes (at RRT start) Non-diabetic 11.2 10.6 12.1 1.7 Type 1 9.6 16.8 2.7 4.4 Type 2 15.5 16.6 3.1 Coronary artery disease (at RRT start) No 9.9 Yes 19.0 17.8 20.3 4.7 Indigenous Non-Indigenous (Aus) 13.5 12.8 14.3 Non-Indigenous (NZ) 15.7 18.3 1.2 Aboriginal /Torres Strait Islanders 9.0 7.5 10.7 3.2 7.1 Maori (in Aus) 3.4 23.8 Maori (in NZ) 16.4 13.8 19.6 2.5 0.9 6.7 Pacific People (in Aus) 6.5 10.3 0.2 9.1 Pacific People (in NZ) 7.9 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.3 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.4 ANZDATA Registry Annual Report 2013

Age Groups at start of treatment Figure 3.5 Survival of Dialysis Patients by Age Age Groups at start of treatment Median (25th and 75th centiles), years   Australia 0-24 years * 25-44 years * (5.35-*) 45-64 years 6.35 (3.09-*) 65-74 years 4.18 (1.90-7.23) 75-84 years 3 (1.31-5.32) 85+ years 2.03 (0.76-4.02) New Zealand 9.64 (8.11-*) 7.28 (4.11-*) 5 (2.65-8.41) 3.65 (1.84-5.93) 2.61 (1.08-4.37) 1.70 (0.96-3.58) ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.6 Survival by Age & Comorbidity Amongst Older Age Groups Median (25th and 75th centiles), years Age Groups Any Vascular Disease Diabetes Australia   New Zealand 65-69 years No 5.32 (2.04-*) 6.01 (2.67-7.68) Yes 3.95 (1.93-8.29) 5.23 (4.20-8.69) 4.30 (2.08-7.04) 2.36 (0.87-4.81) 4.31 (2.05-6.96) 4.03 (1.41-4.27) 70-74 years 5.37 (2.03-8.37) 3.40 (3.12-5.37) 5.89 (3.23-8.38 ) 3.33 (2.27-4.41) 3.46 (0.96-5.81) 2.55 (1.63-4.45) 3.65 (1.80-5.97) 3.33 (1.78-4.88) 75-79 years 5.47 (2.14-8.31) 3.43 (3.43-3.43) 5.59 (2.39-*) 3.92 (3.92-4.39) 4.00 (1.85-6.35) 1.42 (0.57-2.43) 3.08 (1.04-5.48) 2.97 (1.49-5.74) 80-84 years 3.41 (2.02-6.21) 2.69 (1.65-3.01) 4.34 (2.70-6.17) 0.67 (0.67-0.67) 2.28(1.02-4.90) 4.10 (1.04-4.10) 2.37 (1.29-4.55) 2.82 (2.82-2.82) 85-89 years 2.25 (0.63-7.79) * 2.39 (0.63-*) 2.17 (1.32-3.58) 1.38 (1.38-4.91) 1.57 (0.36-6.09) ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.7 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.8 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.9 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.10 ANZDATA Registry Annual Report 2013

Modality at Time of Death and Age at Death – 2012 Figure 3.11 Modality at Time of Death and Age at Death – 2012 Cause of Death Haemodialysis   Peritoneal Dialysis Transplant 0 - 44 45 - 64 65 - 74 ≥75 Australia Cardiovascular 19 113 101 147 5 17 13 29 2 14 20 7 Withdrawal 15 67 88 248 34 3 4 Cancer 1 25 6 Infection 28 30 Other 73 58 110 8 27 11 New Zealand 41 24 16 10 22 12 9 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.12 Country at time of Death and Modality at Death Among Those Who Withdrew From Dialysis and Died in 2012 Cause of Death AUSTRALIA   NEW ZEALAND HD PD GRAFT Cardiovascular 380 64 43 90 53 12 Withdrawal 418 69 16 45 26 1 Cancer 67 9 48 7 6 Infection 94 25 24 19 10 3 Other 255 59 35 63 36 4 ANZDATA Registry Annual Report 2013

Death Due to Withdrawal - 2012 (Modality at Time of Death) Figure 3.13 Death Due to Withdrawal - 2012 (Modality at Time of Death) Withdrawal Haemodialysis Peritoneal Dialysis Transplant Total Australia   Psychosocial 163 26 7 196 Patient refused further 20 4 28 Suicide 5 1 6 Cardiovascular comorbidity 81 13 94 Cerebrovascular comorbidity 43 10 54 Peripheral vascular comorbidity 31 2 33 Malignancy related withdrawal 63 11 77 Withdrawal due to dialysis 12 3 15 418 69 16 503 New Zealand 25 8 14 9 45 72 ANZDATA Registry Annual Report 2013

Time from first RRT (years) Figure 3.14 Dialysis patients who withdrew by age at death time from first RRT-2012 Time from first RRT (years) AUSTRALIA   NEW ZEALAND 0 - 44 45 - 64 65 - 74 ≥75 Total 2 19 16 49 86 3 1 9 15 13 36 66 6 7 48 96 166 8 24 5 34 38 105 185 10 26 83 115 286 503 21 25 72 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013 Figure 3.15 ANZDATA Registry Annual Report 2013

ANZDATA Registry Annual Report 2013