Volume 73, Issue 8, Pages (April 2008)

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Volume 73, Issue 8, Pages 940-946 (April 2008) Early steroid treatment improves the recovery of renal function in patients with drug- induced acute interstitial nephritis E. González, E. Gutiérrez, C. Galeano, C. Chevia, P. de Sequera, C. Bernis, E.G. Parra, R. Delgado, M. Sanz, M. Ortiz, M. Goicoechea, C. Quereda, T. Olea, H. Bouarich, Y. Hernández, B. Segovia, M. Praga Kidney International Volume 73, Issue 8, Pages 940-946 (April 2008) DOI: 10.1038/sj.ki.5002776 Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 1 Correlation between the delay in steroid treatment and final Scr. Kidney International 2008 73, 940-946DOI: (10.1038/sj.ki.5002776) Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 2 Rate of renal function recovery, expressed by a >50% decrease of highest Scr, in Group 1a (final complete recovery of renal function) and Group 1b (incomplete recovery). Kidney International 2008 73, 940-946DOI: (10.1038/sj.ki.5002776) Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 3 Evolution of interstitial infiltrates. Dense interstitial cellular infiltrates in the first renal biopsy of a patient of Group 1b (top). In a second renal biopsy, obtained 33 days later, cellular infiltrates have been largely replaced by fibrotic areas in the interstitium (bottom). Kidney International 2008 73, 940-946DOI: (10.1038/sj.ki.5002776) Copyright © 2008 International Society of Nephrology Terms and Conditions