MASTOR: Mixed-Model Association Mapping of Quantitative Traits in Samples with Related Individuals  Johanna Jakobsdottir, Mary Sara McPeek  The American Journal of Human Genetics  Volume 92, Issue 5, Pages 652-666 (May 2013) DOI: 10.1016/j.ajhg.2013.03.014 Copyright © 2013 The American Society of Human Genetics Terms and Conditions

Figure 1 Power Comparisons between Statistics For each of 60 stimulated scenarios, power was evaluated at four different significance levels: .05, .01, .005, and .001. Results from all 240 settings are represented. Empirical power is based on 25,000 replicates. MASTORG is a version of MASTOR with heritability estimated from group S (the GTAM sample) and GTAMM is a version of GTAM with heritability estimated from R (the MASTOR phenotype sample). For each of the 240 settings, graphs plot (A) the power of MASTOR versus the power of MASTORG, (B) the power of MASTOR versus ASTOR; (C) the power of MASTOR versus GTAMM; (D) the power of ASTOR versus GTAM; (E) the power of GTAM versus GTAMM; and (F) the power of MASTOR versus GTAM. In (C) and (E), a point is blue if the type 1 error of GTAMM was significantly deflated (.05 level) in the corresponding scenario, the point is red if the type 1 error of GTAMM was significantly inflated (.05 level) in the corresponding scenario, and the point is black if the type 1 error of GTAMM was not significantly different from nominal. The American Journal of Human Genetics 2013 92, 652-666DOI: (10.1016/j.ajhg.2013.03.014) Copyright © 2013 The American Society of Human Genetics Terms and Conditions