Ms. Cuthrell Mutations.

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Ms. Cuthrell Mutations

3.1.3 Explain how mutations in DNA that result from interactions with the environment (i.e. radiation and chemicals) or new combinations in existing genes lead to changes in function and phenotype.

Mutations Mutations are changes in DNA coding and can be deletions, additions, or substitutions. Mutations can be random and spontaneous or caused by radiation and/or chemical exposure.

What kind of mutation? Before: TAC CCG GAT ACT After: TAC GCG GAT ACT

What kind of mutation? Before: TAC CCG GAT ACT After: TAC CGG ATA CT

What kind of mutation? Before: TAC CCG GAT ACT After: TAC CCG GAA TAC T

Question Which type of mutation would you think is the least harmful? Why?

Cancer Caused by mutations in somatic (body) cells.

Heritable Changes Only mutations in gametes (egg and sperm) can result in heritable changes. Some mutations can cause a good or bad change in physical appearance. Some cause genetic disorders such as cystic fibrosis, PKU, Huntington’s disease, sickle cell anemia, or hemophilia.