The Simplified Acute Physiology Score II as a Predictor of Mortality in Patients Who Underwent Extracorporeal Membrane Oxygenation for Septic Shock Myung.

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The Simplified Acute Physiology Score II as a Predictor of Mortality in Patients Who Underwent Extracorporeal Membrane Oxygenation for Septic Shock Myung Jin Choi, MD, Sang Ook Ha, MD, Hyoung Soo Kim, MD, PhD, Sunghoon Park, MD, PhD, Sang Jin Han, MD, Sun Hee Lee, APN The Annals of Thoracic Surgery Volume 103, Issue 4, Pages 1246-1253 (April 2017) DOI: 10.1016/j.athoracsur.2016.07.069 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier survival curve for patients who underwent extracorporeal membrane oxygenation (ECMO) for septic shock. The cumulative (Cum) survival rates at 28 days and hospital discharge were 42.9% and 35.7%, respectively. Two patients died in the hospital on days 30 and 37 after ECMO implantation. Ten patients were discharged from the hospital and followed up for a mean of 13.9 months. One patient died 1 month after hospital discharge. The Annals of Thoracic Surgery 2017 103, 1246-1253DOI: (10.1016/j.athoracsur.2016.07.069) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Receiver-operating characteristics (ROC) curve for predictability of Simplified Acute Physiology Score II (SAPS II) for survival to hospital discharge. The area under the ROC curve was 0.80 (95% confidence interval: 0.62 to 0.98, p = 0.010) for SAPS II. The optimal cutoff value of SAPS II was 80 for predicting mortality at hospital discharge. In analysis of SAPS II 80, sensitivity of 83.3%, specificity of 80.0%, positive predictive value of 77.8%, and negative predictive value of 80.0% were noted. The Annals of Thoracic Surgery 2017 103, 1246-1253DOI: (10.1016/j.athoracsur.2016.07.069) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier survival curve for survival to hospital discharge between patients with Simplified Acute Physiology Score II (SAPS II) above 80 (red line) and below 80 (blue line). The cumulative (Cum) survival rate at hospital discharge and at 54-month follow-up was significantly higher for patients with a SAPS II score of 80 or less compared with patients having a SAPS II score greater than 80 (66.7% versus 12.5% and 58.3% versus 12.5%, respectively; p = 0.001). The Annals of Thoracic Surgery 2017 103, 1246-1253DOI: (10.1016/j.athoracsur.2016.07.069) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions