Direct role of HIS-24 and HPL in control of microbial resistance. Direct role of HIS-24 and HPL in control of microbial resistance. (A) Survival assay of mutant animals in infection experiments using the Gram-positive bacterium B. thuringiensis. (B) Survival assays of transgenic worms carrying HIS-24::GFP in the his-24+/+ or his-24−/− background. The presence of the modified form of HIS-24::GFP (HIS-24A14::GFP) did not influence the survival of his-24−/− mutant animals on B. thuringiensis plates. Data are mean survivals (± standard errors of the mean) relative to the wild type. *, P < 0.0001, versus the wild type. Studencka M et al. Mol. Cell. Biol. 2012;32:251-265