Neil Marsh, Department of Chemistry, University of Michigan

Slides:



Advertisements
Similar presentations
Chapter 19 The Chemistry of Life.
Advertisements

The Organic Chemistry of Enzyme-Catalyzed Reactions Revised Edition
Ufedo Ruby Awodi and Greg L. Challis
Microbial Metabolism Chapter 5. Metabolism - all of the chemical reactions within a living organism w 1. Catabolism ( Catabolic ) breakdown of complex.
Chem 3550 Chapter 16: Production of NADH and NADPH: The Citric Acid Cycle, the Glyoxylate Cycle (Skip), and the Pentose Phosphate Pathway.
2.4 Chemical Reactions and Enzymes Standard B.1.2
Chemical Reactions & Enzymes. I. Chemistry A. We already know that all living things are made up of chemical compounds. What are they again? Which give.
Chemical reactions and enzymes 2.4. Chemical reactions Change one substance into another Involve changes to the chemical bonds that hold molecules together.
Connect Why do we spend time in biology studying chemicals? Why do we have to eat? What happens to the food we eat? What organic molecules did you eat.
Chemical Reactions & Enzymes - Means to write that information down. - Means to write that information down.
Chemical Reactions and Enzymes
Enzyme and Energy Review. Enzyme Enzymes are catalytic molecules. That is, they speed up specific reactions without being used up in the reaction. Enzymes.
THE CALVIN CYCLE Section Carbon Fixation by the Calvin Cycle The Second set of reactions in photosynthesis involves a biochemical pathway known.
What our bodies are made of Chemistry of Cells. Nature of Matter All matter is made of atoms. Atoms consist of electrons, protons and neutrons. Molecules.
Enzymes Catalyze (speed up) reactions Recognize and bind specific substrates Act repeatedly Most are proteins Reaction does not alter them.
A Lock-and-Key Enzyme Animation. Enzyme Substrate Active Site.
Chemical Reactions and Enzymes Chemistry isn’t just what life is made of; it’s also what life does.
ENZYME NOTES. Chemical Reactions Chemical Reaction – process that changes one set of chemicals into another set of chemicals Reactants – elements or compounds.
Chapter 4: Cellular Metabolism Part I: Metabolic Processes Control of Metabolic Reactions.
What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)
CHEMICAL REACTIONS!!!! reactant + reactant  product reactant  product + product reactant + reactant  product + product What are some other ways that.
Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
F5 Metabolism of Microbes By Matt Oda, Ross Tanaka, and Tia Rosehill.
Chemistry of Life Biology chapter 2.4. Enzymes (Proteins)  Enzymes are proteins that act as catalysts in nearly all metabolic processes (essential for.
Enzymes. Enzymes-definition  Act as catalysts, lowering activation energy needed for reactions-speed up reaction.  Substrate binds to enzyme’s active.
 Plants  Protists (Algae, Euglena) Euglena Algae on Water.
The next 2 slides are part of one question.. Which of the following is not a step in the mechanism of the given reaction?
Macromolecules and Enzymes. Enzymes Enzymes – biological catalysts used to speed up reactions The reaction may still occur without an enzyme present,
Enzyme kinetics & Michaelis-Menten Equation Abdul Rehman Abbasi MSc Chemistry Semester – I Preston University Isb.
The Chemistry of Living Things
Organic Compounds.
Methylation Methylation with methyl group transfer from S-adenosyl methionine, although feasible, is not an important pathway for drug metabolism. Methylation.
Increasing Absorption Range for Photosynthesis
Activity test Creative Enzymes performs the most reliable measurement of enzyme activities for a variety of application purposes. The unique technology.
Enzyme o/a lets see what you can remember 
Dehydrogenase In enzymology, a D-lactate dehydrogenase is an enzyme that catalyzes the chemical reaction: (D)- lactate + 2 ferricytochrome c↔ pyruvate.
ENZYMES are proteins that catalyze [start/speed up] chemical reactions
Chemical reactions and enzymes
Section 2-4 Chemical Reactions and Enzymes (pages 49-53)
Vitamin B6 is a water-soluble vitamin and is part of the vitamin B complex group. Several forms of the vitamin are known, but pyridoxal phosphate (PLP)
Acyl-coa oxidase In enzymology, an acyl-CoA oxidase (EC ) is an enzyme that catalyzes the chemical reaction acyl-CoA + O2↔ trans-2, 3-dehydroacyl-CoA.
Biological compounds The chemistry of living organisms
Enzyme Review.
Enzyme Review.
KEY CONCEPT Life depends on chemical reactions.
Lesson 2.4: Chemical Reactions & Enzymes
Enzymes Page 23.
Ch 6 Section 2 Enzymes.
Chemical Reactions and Enzymes
الفعل ورد الفعل ♠ ♠ ♠ مجلس أبوظبي للتعليم منطقة العين التعليمية
Nickel-Catalyzed Polymerizations: Mechanistic Studies & New Reaction Development Anne J. McNeil Department of Chemistry and Macromolecular Science and.
Enzymes: Outcome: I can describe how the structure of an enzyme correlates to its function(s) Drill: What background knowledge do you have on enzymes?
Enzymes Biology.
BIO231 Flash Cards for Raven Chapter 6b
2.4: Chemical Reactions & Enzymes
2.4 Chemical Reactions and Enzymes
Chemistry 24.1.
Small Molecules, Big Effects: A Role for Chromatin-Localized Metabolite Biosynthesis in Gene Regulation  Bryan A. Gibson, W. Lee Kraus  Molecular Cell 
Enzymes.
Enzymes Biology.
February 12, 2002 Chapter 26 Nitrogen Acquisition
KEY CONCEPT Enzymes are catalysts for chemical reactions in living things.
The Chemistry of Life Chapter 2 Part 2.
Chemistry of Life Enzymes
Chapter 2.4 Enzymes.
Learning Objectives Define the following terms: enzyme, chemical reaction, reactant, product, activation energy, catalyst, enzyme-substrate complex. Describe.
Enzymes 2nd year Biology department
Chapter 2 The Chemistry of Life.
Development of Transition Metal Catalysts for
Chemistry of Living Things
Presentation transcript:

Aldehyde Decarbonylase : a Novel Enzyme Involved in Hydrocarbon Biosynthesis Neil Marsh, Department of Chemistry, University of Michigan Aldehyde decarbonylase catalyzes and unusual reaction involving the release of carbon monoxide about which nothing is known mechanistically Two quite different forms of the enzyme are known: a membrane-bound form in plants and algae, and a soluble form found in cyanobacteria We have over expressed both forms of the enzyme in E. coli and are currently investigating the cofactor requirements and substrate specificity of the enzyme