Plagiarism and Pathogenesis Robin C. May, Laura M. Machesky Developmental Cell Volume 1, Issue 3, Pages 317-318 (September 2001) DOI: 10.1016/S1534-5807(01)00051-X
Figure 1 Comparison of the Signals Used by Vaccinia and EPEC to Generate Actin Tails and Pedestals, Respectively Both pathogens use a common core mechanism, involving the binding of Nck to a phosphorylated tyrosine residue, to activate WASP family proteins and thus the Arp2/3 complex. In the case of the EPEC Tir protein, additional domains anchor the complex to the cytoskeleton via α-actinin, maintaining bacterial attachment Developmental Cell 2001 1, 317-318DOI: (10.1016/S1534-5807(01)00051-X)