Robert J. Rizzo, MD, Walter J. McCarthy, MD, Saryu N

Slides:

Advertisements

Similar presentations

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,

Advertisements

The effect of inguinal lymphatic manipulation on regional lymph flow patterns Jeffrey R. Rubin, MD, Lisa B. Eberlin, MD Journal of Vascular Surgery Volume.

Aortic injury occurring after minor trauma in ankylosing spondylitis

Nondissecting aneurysm of the thoracic aorta with arteritis in systemic lupus erythematosus Hisato Takagi, MD, PhDa, Yoshio Mori, MD, PhDa, Hisashi Iwata,

Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type Stuart K. Williams,

Hospital vascular surgery volume and procedure mortality rates in California, Larry M. Manheim, PhD, Min-Woong Sohn, PhD, Joe Feinglass, PhD,

Ultrasound measurement of the luminal diameter of the abdominal aorta and iliac arteries in patients without vascular disease Ole Martin Pedersen, MD,

Abdominal duplex ultrasound screening for occult aortic aneurysm during carotid arterial evaluation George A. Carty, MD, Tom Nachtigal, MD, Rose Magyar,

Robert J. Pitsch, MD, David J. Minion, MD, Margaret L

Endogenous superoxide dismutase activation by oral administration of riboflavin reduces abdominal aortic aneurysm formation in rats Zhenhai Yu, MD, Keisuke.

Richard T. Purdy, M. D. , Frederick C. Beyer, M. D. , William D

Christopher K. Zarins, MD, Chengpei Xu, MD, Seymour Glagov, MD

Chang M. He, MSc, Margot R. Roach, MD, PhD Journal of Vascular Surgery

Gastroesophageal tumor embolization to the popliteal arteries

Anti–VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates Alan B. Lumsden, MB, ChB, Changyi Chen,

Duplex ultrasound measurement of changes in mesenteric flow velocity with pharmacologic and physiologic alteration of intestinal blood flow in man Michael.

Atherosclerotic aneurysm formation in an in situ saphenous vein graft

Indomethacin inhibits expansion of experimental aortic aneurysms via inhibition of the cox2 isoform of cyclooxygenase Manuel Miralles, MD, William Wester,

Aortic injury occurring after minor trauma in ankylosing spondylitis

PC222. Loss of Normal Fiber Orientation in Human Abdominal Aortic Aneurysmal Tissue and Increased Energy Loss Sandra Toth, BS, Doran Mix, MD, BS, Ibrahima.

Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: Preservation of aortic elastin associated.

Dennis R. Holmes, MD, William Wester, BA, Robert W

Richard R. Keen, MD, Kevin D

Elastase-induced matrix degradation in arterial organ cultures: An in vitro model of aneurysmal disease Andrew Wills, BSc, Matthew M. Thompson, MD, FRCS,

Suzanne Menashi, Ph. D. , Juan S. Campa, B. Sc. , Roger M

Malcolm O. Perry, MD, Richard Kempczinski, MD

Adventitial elastolysis is a primary event in aneurysm formation

Doxycycline inhibits elastin degradation and reduces metalloproteinase activity in a model of aneurysmal disease Jonathan R. Boyle, FRCS, Edward McDermott,

Rupture of a nonaneurysmal atherosclerotic infrarenal aorta

A novel rat model of abdominal aortic aneurysm using a combination of intraluminal elastase infusion and extraluminal calcium chloride exposure Akiko.

William W. Lin, BA, Gregory S. McGee, MD, Bruce K

John S. Cargile, M. D. , Daniel F. Fisher, M. D. , Dennis K. Burns, M

The temporal relationship between the development of vein graft intimal hyperplasia and growth factor gene expression John R. Hoch, MD, Vida K. Stark,

James E. Chapman, M.D., William Allen Loy, M.D.

Frank A. Lederle, MD, Gary R. Johnson, MS, Samuel E. Wilson, MD, Ian L

Bacterial resistance of refrigerated and cryopreserved aortic allografts in an experimental virulent infection model Pierre-Yves Litzler, MD, Pascale.

Anti–VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates Alan B. Lumsden, MB, ChB, Changyi Chen,

William Fiore, M. D. , Thomas E. Penn, M. D. , Timothy Quill, M. D

Multiple idiopathic arterial aneurysms in children: A case report and review of the literature Vivienne Halpern, MD, James O'Connor, MD, Marianne Murello,

Objective tinnitus resulting from internal carotid artery stenosis

Jae-Sung Cho, MD, Peter Gloviczki, MD, Eugenio Martelli, MD, W

Primary leiomyosarcoma of the abdominal aorta

S.Amjad Hussain, MD, FRCSC, Ahmet Bayar, MD

B. Timothy Baxter, MD, Gregory S. McGee, MD, Vera P

Immunosuppressive treatment of aortic allografts

The lack of type III collagen in a patient with aneurysms and an aortic dissection Kimikazu Hamano, MD, Takayuki Kuga, MD, Mutsuo Takahashi, MD, Kentaro.

The matrix metalloproteinase inhibitor BB-94 limits expansion of experimental abdominal aortic aneurysms David A. Bigatel, MD, James R. Elmore, MD, David.

Calvin B. Ernst, MD Journal of Vascular Surgery

Ruptured abdominal aortic aneurysm: A population-based study

Mesenteric venous thrombosis

Ramesh Lokanathan, MD, FRCS(C), David C. Taylor, MD, FRCS(C)

Thoracoabdominal aortic aneurysm in Cogan’s syndrome

Differential effects of a gram-negative and a gram-positive infection on autogenous and prosthetic grafts Kevin J. Geary, MD, Zygmunt M. Tomkiewicz,

Aortic blebs: Possible site of aneurysm rupture

Research and research funding in vascular surgery

Abdominal aortic aneurysm: Results of a family study

J.Dennis Baker, MD Journal of Vascular Surgery

Excimer laser—assisted femoral angioplasty: Early results

Extended use of computed tomography in the management of complex aortic problems: A learning experience Larry R. Williams, M.D. *, William R. Flinn,

William H. Pearce, MD, Iliana Sweis, MD, James S. T. Yao, MD, Walter J

Malignant fibrous histiocytoma of the aorta

Presidential address: The second-generation vascular surgeon

Wayne Reichman, MD, Cornelius Dyke, MD, H. M

George D. Lilly 1906–1988 Journal of Vascular Surgery

Janet Powell, MD, Roger M. Greenhalgh, MD Journal of Vascular Surgery

James A. DeWeese, MD Journal of Vascular Surgery

Samuel S. Ahn, MD, Robert B. Rutherford, MD, K

A novel rat model of abdominal aortic aneurysm using a combination of intraluminal elastase infusion and extraluminal calcium chloride exposure Akiko.

Endovascular repair of two abdominal aortic aneurysms

Cornelius A. Sullivan, MD, Michael J. Rohrer, MD, Bruce S. Cutler, MD

Presentation transcript:

Collagen types and matrix protein content in human abdominal aortic aneurysms Robert J. Rizzo, MD, Walter J. McCarthy, MD, Saryu N. Dixit, PhD a, Michael P. Lilly, MD, Vera P. Shively, MS, William R. Flinn, MD, James S.T. Yao, MD, PhD Journal of Vascular Surgery Volume 10, Issue 4, Pages 365-373 (October 1989) DOI: 10.1016/0741-5214(89)90409-6 Copyright © 1989 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 a, Carboxymethyl-cellulose chromatography of a CB digestion of abdominal aortic aneurysm. The peak labeled CB8 was pooled for separation by agarose A-1.5 m chromatography. b, Agarose A-1.5 m molecular sieve chromatography of the CB peptides eluting in the CB8 region from carboxymethyl-cellulose. The collagen peptides α1(I)-CB(8-3), α1(I)-CB8, and α1(III)-CB8 eluted from the column at positions corresponding to molecular weight of 37,000, 24,000, and 12,000, respectively. Peak areas were used to calculate the ratios of type I and type III collagens. Journal of Vascular Surgery 1989 10, 365-373DOI: (10.1016/0741-5214(89)90409-6) Copyright © 1989 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Collagen and elastin concentration of infrarenal aorta from nonaneurysmal age-matched control subjects and abdominal aortic aneurysms, expressed as percentage delipidized, decalcified dry weight. Collagen weight was derived from hydroxyproline analysis. Journal of Vascular Surgery 1989 10, 365-373DOI: (10.1016/0741-5214(89)90409-6) Copyright © 1989 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 A, Hematoxylin-eosin stain of infrarenal aorta from a nonaneurysmal age-matched control subject.B, A routine abdominal aortic aneurysm oriented with the intima superiorly and the adventitia inferiorly. Note the infiltration of inflammatory cells particularly within the adventitia of the aneurysm. (Original magnification × 16.) Journal of Vascular Surgery 1989 10, 365-373DOI: (10.1016/0741-5214(89)90409-6) Copyright © 1989 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 A, Elastin van Gieson stain of infrarenal aorta from nonaneurysmal age-matched control subject.B, Abdominal aortic aneurysm oriented with the intima superiorly and the adventitia inferiorly. Note the deficiency and fragmentation of elastin (black) in the aneurysm. (Original magnification × 16.) Journal of Vascular Surgery 1989 10, 365-373DOI: (10.1016/0741-5214(89)90409-6) Copyright © 1989 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions