Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate:
Knee osteoarthritis patients with severe nocturnal pain have altered proximal tibial subchondral bone mineral density  W.D. Burnett, S.A. Kontulainen,
T1ρ and T2 relaxation times predict progression of knee osteoarthritis
Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee  S. Reiter-Niesert, M. Boers, J. Detert 
Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.
Dr L. S. Kim, N. D. , Dr L. J. Axelrod, N. D. , Dr P. Howard, M. D
Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training  S.G. Petersen, T. Saxne, D. Heinegard,
One year effectiveness of neuromuscular exercise compared with instruction in analgesic use on knee function in patients with early knee osteoarthritis:
Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,
Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials  M. Fransen, S.
Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee.
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative 
Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.
Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative 
C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study  G. Engström, M.D., Ph.D.,
Tenascin-C levels in synovial fluid are elevated after injury to the human and canine joint and correlate with markers of inflammation and matrix degradation 
B. F. Riecke, R. Christensen, S. Torp-Pedersen, M. Boesen, H
Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,
D. J. Hunter, D. P. Beavers, F. Eckstein, A. Guermazi, R. F. Loeser, B
J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D. 
Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients.
Osteoarthritis and Cartilage
J. Ranstam  Osteoarthritis and Cartilage 
Subregional femorotibial cartilage morphology in women – comparison between healthy controls and participants with different grades of radiographic knee.
Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial  M. Henriksen, D.J.
Changes in ultrasound assessed markers of inflammation following intra-articular steroid injection combined with exercise in knee osteoarthritis: exploratory.
A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee 
Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain  J. Cibere,
Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3years –
Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.
Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative  S. Maschek,
Weight loss is effective for symptomatic relief in obese subjects with knee osteoarthritis independently of joint damage severity assessed by high-field.
Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression  P.T. Paradowski, L.S. Lohmander, M. Englund 
Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:
Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis  M. Blagojevic, C. Jinks, A. Jeffery, K.P.
G. Neumann, D. Hunter, M. Nevitt, L. B. Chibnik, K. Kwoh, H. Chen, T
Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials  E.M. Bartels, V.N. Folmer, H. Bliddal,
The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial  N.K. Arden, S. Cro, S. Sheard, C.J. Doré,
Poor replicability of recommended exercise interventions for knee osteoarthritis: a descriptive analysis of evidence informing current guidelines and.
D.J. Hunter  Osteoarthritis and Cartilage 
Comparing clinical outcomes of exercise intervetions according to the American college of sports medicine guidelines for strength training to other types.
Comparing two low-energy diets for the treatment of knee osteoarthritis symptoms in obese patients: a pragmatic randomized clinical trial  B.F. Riecke,
Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial 
A novel method for assessing signal intensity within infrapatellar fat pad on MR images in patients with knee osteoarthritis  M. Lu, Z. Chen, W. Han,
Effectiveness of an Ayurveda treatment approach in knee osteoarthritis – a randomized controlled trial  C.S. Kessler, K.S. Dhiman, A. Kumar, T. Ostermann,
D.J. Hunter  Osteoarthritis and Cartilage 
The association between hip bone marrow lesions and bone mineral density: a cross- sectional and longitudinal population-based study  H. Ahedi, D. Aitken,
Osteoarthritis and Cartilage
Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients.
Preoperative progressive explosive-type resistance training is feasible and effective in patients with hip osteoarthritis scheduled for total hip arthroplasty.
Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group  J.A. Zeni, L. Snyder-Mackler  Osteoarthritis.
Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.
Osteoarthritis year 2012 in review: biology
The effect of quadriceps-strengthening exercise on quadriceps and knee biomichanics during walking in adults with knee osteoarthritis: a randomized controlled.
L.A. Deveza, L. Melo, T.P. Yamato, K. Mills, V. Ravi, D.J. Hunter 
L.S. Gates, C.J. Bowen, M.T. Sanchez-Santos, A. Delmestri, N.K. Arden 
G. Blumenkrantz, B. S. , R. Stahl, M. D. , J. Carballido-Gamio, Ph. D
Differences in trabecular bone texture between knees with and without radiographic osteoarthritis detected by directional fractal signature method  M.
Longitudinal assessment of femoral knee cartilage quality using contrast enhanced MRI (dGEMRIC) in patients with anterior cruciate ligament injury – comparison.
Variations in pain and function before and after total knee arthroplasty: a comparison between Swedish and Australian cohorts  M.M. Dowsey, O. Robertsson,
Patient education with or without manual therapy compared to a control group in patients with osteoarthritis of the hip. A proof-of-principle three-arm.
Osteoarthritis year in review 2016: mechanics
The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative  K.L. Paterson, J.
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
Effect of a 16 weeks weight loss program on osteoarthritis biomarkers in obese patients with knee osteoarthritis: a prospective cohort study  E.M. Bartels,
Association between bone marrow lesions detected by magnetic resonance imaging and knee pain in community residents in Korea  I.J. Kim, D.H. Kim, J.Y.
General Information Osteoarthritis and Cartilage
Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis 
Presentation transcript:

Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary outcome analyses from a randomized controlled trial  M. Henriksen, R. Christensen, D.J. Hunter, H. Gudbergsen, M. Boesen, L.S. Lohmander, H. Bliddal  Osteoarthritis and Cartilage  Volume 22, Issue 5, Pages 639-646 (May 2014) DOI: 10.1016/j.joca.2014.03.003 Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Enrollment of patients and completion of the study. Osteoarthritis and Cartilage 2014 22, 639-646DOI: (10.1016/j.joca.2014.03.003) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 MR-images from a representative case showing longitudinal change in BMLs. Top row images are baseline images. Bottom row images are images obtained at week 68. Note the progression of and increased number of BMLs in the posterior part of the medial femoral condyle (arrows). Osteoarthritis and Cartilage 2014 22, 639-646DOI: (10.1016/j.joca.2014.03.003) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions