Sidhu P. Gangadharan, BS, Robert J. Wagner, BS, Jack L. Cronenwett, MD

Slides:

Advertisements

Similar presentations

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,

Advertisements

The role of arteriovenous shunts in the pathogenesis of varicose veins Howard C. Baron, M.D., Sebastiano Cassaro, M.D. Journal of Vascular Surgery Volume.

Platelet survival and serotonin content after placement of arterial prostheses in dogs: Effects of neointimal coverage and high- and low-dose aspirin G.Patrick.

The effect of inguinal lymphatic manipulation on regional lymph flow patterns Jeffrey R. Rubin, MD, Lisa B. Eberlin, MD Journal of Vascular Surgery Volume.

Acute mesenteric ischemia after cardiopulmonary bypass

Aortic injury occurring after minor trauma in ankylosing spondylitis

Matthew R. Quigley, M. D. , Julian E. Bailes, M. D. , Hau C. Kwaan, M

Martorell's hypertensive ischemic leg ulcers are secondary to an increase in the local vascular resistance Henry J. Duncan, B.M., B.S., Irwin B. Faris,

William B. Schroder, MD, John F. Bealer, MD

Robert J. Pitsch, MD, David J. Minion, MD, Margaret L

Value of single photon emission computerized imaging in the treatment of patients undergoing carotid endarterectomy Roy L. Tawes, MD, Robert Lull, MD

Gastroesophageal tumor embolization to the popliteal arteries

Presidential address: Energy, poise, and resilience—Daniel Bernoulli, Thomas Young, J. L. M. Poiseuille, and F. A. Simeone Robert W. Hopkins, MD Journal.

A percutaneous arterial closure protocol can decrease complications after endovascular interventions in vascular surgery patients Philip P. Goodney,

Surgical management of infected abdominal aortic grafts: Review of a 25-year experience Patrick J. O'Hara, M.D., Norman R. Hertzer, M.D., Edwin G. Beven,

A new valvulotome for in situ bypass grafts

Aortic injury occurring after minor trauma in ankylosing spondylitis

Prevention of ischemic spinal cord injury: Comparative effects of magnesium sulfate and riluzole Loïc Lang-Lazdunski, MD, Catherine Heurteaux, PhD, Hervé.

Harry L. Bush, M. D. , Joseph A. Jakubowski, Ph. D. , G

Development of a computerized vascular registry for large-scale use

Mark F. Fillinger, MD, Susan E. O'Connor, MD, Robert J

The neuroprotective effects of intrathecal administration of the selective N-type calcium channel blocker ziconotide in a rat model of spinal ischemia

John Blebea, MD, John C. Kerr, BA, Charles D. Franco, MD, Frank T

Malcolm O. Perry, MD, Richard Kempczinski, MD

William W. Lin, BA, Gregory S. McGee, MD, Bruce K

Minimal physiologic temperature variations during renal ischemia alter functional and morphologic outcome Timothy J. Pelkey, BS, Richard S. Frank, MD,

Aortic collagenase activity as affected by laparotomy, cecal resection, aortic mobilization, and aortotomy in rats Jon R. Cohen, M.D., Malcolm O. Perry,

John Blebea, MD, Robert A. Cambria, MD, David DeFouw, PhD, Richard N

Objective tinnitus resulting from internal carotid artery stenosis

Robert A. McCready, M. D. , Margaret A. Price, B. S. , Richard J

The effect of ischemia/reperfusion on adenine nucleotide metabolism and xanthine oxidase production in skeletal muscle Thomas F. Lindsay, MD, Shinta.

Controlled delivery of vascular endothelial growth factor promotes neovascularization and maintains limb function in a rabbit model of ischemia Steven.

Glossopharyngeal nerve injury complicating carotid endarterectomy

Determinants of ischemic injury to skeletal muscle

Current use of inferior vena cava filters

Glucagon potentiates intestinal reperfusion injury

Calvin B. Ernst, MD Journal of Vascular Surgery

Matthew R. Quigley, M. D. , Julian E. Bailes, M. D. , Hau C. Kwaan, M

Mesenteric blood flow in patients with diabetic neuropathy

Value of single photon emission computerized imaging in the treatment of patients undergoing carotid endarterectomy Roy L. Tawes, MD, Robert Lull, MD

John Hunter—triumph and tragedy

Cardiovascular surgery—The rocket and its stars: Presidential address

Dipyridamole-thallium scintigraphy predicts perioperative and long-term survival after major vascular surgery Bruce S. Cutler, MD, Robert C. Hendel,

Composite sequential bypasses to the ankle and beyond for limb salvage

Research and research funding in vascular surgery

Ischemia-reperfusion injury of the spinal cord: Protective effect of the hydroxyl radical scavenger dimethylthiourea Willem Wisselink, MD, Samuel R.

J.Dennis Baker, MD Journal of Vascular Surgery

Protective effect of glycine in mesenteric ischemia and reperfusion injury in a rat model Sreedhar Kallakuri, MD, Enrico Ascher, MD, Murali Pagala, PhD,

Substitution by adenosine for glucagon as a surgical diagnostic tool to detect mesenteric vascular adaptation István Dóbi, MD, Alexander Juhász-Nagy,

Jay B. Fisher, MD, Marc A. Granson, MD Journal of Vascular Surgery

Thomas N. Ahlborn, M.D., John D. Birkhoff, M.D., Roman Nowygrod, M.D.

Should patient age be a consideration in carotid endarterectomy?

Exposure of femoral vessels by a suprainguinal incision

Heparin prevents postischemic endothelial cell dysfunction by a mechanism independent of its anticoagulant activity* W.Charles Sternbergh, MD, Raymond.

Monitoring vascular surgical performance

Glenn C. Hunter, M.D., Stan N. Carson, M.D.

Infectious aneurysm of a mesenteric artery branch in a youngpatient

Intragraft drug infusion as an adjunct to balloon catheter thrombectomy for salvage of thrombosed infragenicular vein grafts: A preliminary report Daniel.

D. Emerick Szilagyi, MD—An appreciation

Toll-like receptor 4 inhibition attenuates ischemia-reperfusion injury in rats: Will it work in human beings? Chadrick E. Denlinger, MD The Journal.

Superficial temporal artery aneurysms

Presidential address: The second-generation vascular surgeon

George D. Lilly 1906–1988 Journal of Vascular Surgery

James A. DeWeese, MD Journal of Vascular Surgery

Jerry Goldstone, MD Journal of Vascular Surgery

Fate of the contralateral leg after infrainguinal bypass

Innominate artery trauma: A thirty-year experience

Popliteal entrapment syndrome: A report of tibial nerve entrapment

A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia- reperfusion in mice Alik Farber, MD, John P. Connors, MD, Robert.

Cornelius A. Sullivan, MD, Michael J. Rohrer, MD, Bruce S. Cutler, MD

Presentation transcript:

Effect of intravenous glucagon on intestinal viability after segmental mesenteric ischemia Sidhu P. Gangadharan, BS, Robert J. Wagner, BS, Jack L. Cronenwett, MD Journal of Vascular Surgery Volume 21, Issue 6, Pages 900-908 (June 1995) DOI: 10.1016/S0741-5214(95)70217-2 Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Quantitative measurements of ileal ischemic-reperfusion injury performed by digitizing projected microscopic image with computerized planimeter. a, Muscularis thickness; b, mucosal thickness; c, transmural thickness (each measured at 30 points around circumference in each section); d, percentage of luminal circumference covered with mucosal epithelial cells; e, villar surface circumference measured and divided by bowel circumference at base of villi f, to calculate villar surface ratio. Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Representative transverse sections from nonischemic ileum (A) and ileum after 110 minutes of ischemia and 24 hours of reperfusion in (B) glucagon-treated and (C) control rats. Control rats showed near-total mucosal loss, with absent epithelial coverage (C), whereas glucagon-treated rats showed more mucosal preservation with epithelium often intact (B). (Original magnification ×160.) Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Representative transverse sections from nonischemic ileum (A) and ileum after 110 minutes of ischemia and 24 hours of reperfusion in (B) glucagon-treated and (C) control rats. Control rats showed near-total mucosal loss, with absent epithelial coverage (C), whereas glucagon-treated rats showed more mucosal preservation with epithelium often intact (B). (Original magnification ×160.) Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Representative transverse sections from nonischemic ileum (A) and ileum after 110 minutes of ischemia and 24 hours of reperfusion in (B) glucagon-treated and (C) control rats. Control rats showed near-total mucosal loss, with absent epithelial coverage (C), whereas glucagon-treated rats showed more mucosal preservation with epithelium often intact (B). (Original magnification ×160.) Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Comparison of ileal mucosal thickness in control and glucagon-treated rats after segmental mesenteric ischemia (mean ± SEM). Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Comparison of percentage of mucosa covered by epithelium in control and glucagon-treated rats after segmental mesenteric ischemia (mean ± SEM). Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Comparison of villar surface ratio of ileal mucosa in control and glucagon-treated rats after segmental mesenteric ischemia (mean ± SEM). Journal of Vascular Surgery 1995 21, 900-908DOI: (10.1016/S0741-5214(95)70217-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions