Rescue of the Mucocutaneous Manifestations in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa (RDEB) By Human Cord Blood Derived Unrestricted.

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Rescue of the Mucocutaneous Manifestations in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa (RDEB) By Human Cord Blood Derived Unrestricted Somatic Stem Cells (USSCs) Ahmed Rashad, BS, Larisa Ivanova, PhD, Yanling Liao, PhD, Mitchell S. Cairo, MD Biology of Blood and Marrow Transplantation Volume 21, Issue 2, Pages S240-S241 (February 2015) DOI: 10.1016/j.bbmt.2014.11.374 Copyright © 2015 Terms and Conditions

Figure 1 (A). Skin phenotypes of a RDEB mouse after birth (DO), on D7 and D16 demonstrating amelioration of hemorrhagic blisters following a single USSC intrahepatic treatment. (B). Kaplan-Meier survival curves of the RDEB mice that received PBS, a single intrahepatic USSC and repeated intrahepatic USSC injections. (C). H&E staining of the paws of RDEB mice on different days following a single USSC intrahepatic injection. Biology of Blood and Marrow Transplantation 2015 21, S240-S241DOI: (10.1016/j.bbmt.2014.11.374) Copyright © 2015 Terms and Conditions