Evolving characteristics of toxoplasmosis in patients infected with human immunodeficiency virus-1: clinical course and Toxoplasma gondii-specific immune.

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Presentation transcript:

Evolving characteristics of toxoplasmosis in patients infected with human immunodeficiency virus-1: clinical course and Toxoplasma gondii-specific immune responses C. Hoffmann, M. Ernst, P. Meyer, E. Wolf, T. Rosenkranz, A. Plettenberg, A. Stoehr, H.-A. Horst, K. Marienfeld, C. Lange Clinical Microbiology and Infection Volume 13, Issue 5, Pages 510-515 (May 2007) DOI: 10.1111/j.1469-0691.2007.01683.x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Cumulative overall survival of patients diagnosed with toxoplasmic encephalitis at different time periods. Clinical Microbiology and Infection 2007 13, 510-515DOI: (10.1111/j.1469-0691.2007.01683.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 ELISPOT results, either unstimulated (unst.), stimulated with soluble Toxoplasma gondii antigens alone, or co-stimulated with interleukin (IL)-12 or IL-15, respectively, for group A (left, five patients with an acute toxoplasmic encephalitis (TE) episode) and for group B (right, seven patients who did not develop a TE relapse within 12 months of discontinuation of maintenance therapy). PBMCs, peripheral blood mononuclear cells. Clinical Microbiology and Infection 2007 13, 510-515DOI: (10.1111/j.1469-0691.2007.01683.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions