Impact of an evidence-based guideline on the management of community-acquired bacterial meningitis: a prospective cohort study J.M. Costerus, M.C. Brouwer,

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Impact of an evidence-based guideline on the management of community-acquired bacterial meningitis: a prospective cohort study J.M. Costerus, M.C. Brouwer, M.W. Bijlsma, M.W. Tanck, A. van der Ende, D. van de Beek Clinical Microbiology and Infection Volume 22, Issue 11, Pages 928-933 (November 2016) DOI: 10.1016/j.cmi.2016.07.026 Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Percentage frequency of diagnostic or therapeutic interventions bacterial meningitis per period (March 2006 to January 2015, divided into periods of 211 to 218 days). Dotted line, predicted course without introduction of guideline; solid line, actual frequency; vertical line, publication of guideline. AB, antibiotics; CT, computed tomography of brain; LP, lumbar puncture. Clinical Microbiology and Infection 2016 22, 928-933DOI: (10.1016/j.cmi.2016.07.026) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions