Schematic of the Q-OT-qIT hybrid mass spectrometer (Fusion).

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Schematic of the Q-OT-qIT hybrid mass spectrometer (Fusion). Schematic of the Q-OT-qIT hybrid mass spectrometer (Fusion). The system differs from previous generations of quadrupole ion trap/Orbitrap hybrids by introduction of a resolving quadrupole mass filter and rearrangement of the geometry to place the linear ion traps to the rear of the collision cell. The reconfigured geometry relieves the linear ion trap of two of its former functions—precursor ion isolation and dissociation. The consequence is both improved and faster operation. Alexander S. Hebert et al. Mol Cell Proteomics 2014;13:339-347 © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.