Muscles
Muscle Overview The three types of muscle tissue are skeletal, cardiac, and smooth These types differ in structure, location, function, and means of activation PLAY InterActive Physiology ®: Anatomy Review: Skeletal Muscle Tissue, page 3
Muscle Images
Sarcomere surrounded by sarcoplasmic reticulum
sarcomere contraction animation myofilament contraction__ sliding-filament-theory
Sliding Filament Theory Order the following events in sequence to explain the contraction of skeletal muscle. ____ Ca+2 binds to troponin/tropomyosin (regulatory proteins) which opens myosin binding sites on actin. ____ As ADP and P leave the myosin head, it swivels forward pulling the actin filament toward the center of the sarcomere. The sarcomere shortens. ____ An action potential moving through the sarcolemma (what is this?) stimulates release of Ca+2 from the sarcoplasmic reticulum.(what is this?) ____ Myosin heads (activated by the breakdown of ATP) bind to exposed sites on the actin filament. ____ ATP binds to the myosin head and it relaxes, falling away from the actin filament. _____ Cycle repeats until Ca2+ or ATP are withdrawn.
Events at Neuromuscular Junction
Events at Neuromuscular Junction Action potential in the nerve is activated Ca2+ runs into the nerve Ach is released into the synaptic cleft Ach binds to receptors on the muscle Na runs into the muscle Action potential runs across the muscle and into the T tubules Enzymes break Ach into Acetic Acid and Choline
Anatomy and Physiology How a muscle contracts - Neuromuscular Junction/Sliding Filament Theory View the following websites to consolidate your understanding of the events at the neuromuscular junction and the sliding filament theory of muscle contraction. : http://www.blackwellpublishing.com/matthews/nmj.html http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter10/animation__function_of_the_neuromuscular_junction__quiz_3_.html http://bcs.whfreeman.com/thelifewire/content/chp44/4403s.swf http://media.pearsoncmg.com/bc/bc_0media_ap/apflix/ap/ap_video_player.html?tnj
Do Now – Muscle #1 Describe the structure and function of the three types of muscle tissue. Draw sarcomere from a skeletal muscle cell-show the arrangement of the thin and thick filaments and label the sections of the sarcomere.
Muscle Contraction View the following websites to consolidate your understanding of the events at the neuromuscular junction and the sliding filament theory of muscle contraction. Neuromuscular junction: http://media.pearsoncmg.com/bc/bc_0media_ap/apflix/ap/ap_video_player.html?tnj http://www.blackwellpublishing.com/matthews/nmj.html http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter10/animation_function_of_the_neuromuscular_junction__quiz_3_.html Inside the muscle fiber: www.blackwellpublishing.com/matthews/myosin.html http://bcs.whfreeman.com/thelifewire/content/chp47/4702001.html www.blackwellpublishing.com/matthews/myosin.html