Examination of Mutations in BRAF, NRAS, and PTEN in Primary Cutaneous Melanoma  Vikas K. Goel, Alexander J.F. Lazar, Carla L. Warneke, Mark S. Redston, Frank G. Haluska  Journal of Investigative Dermatology  Volume 126, Issue 1, Pages 154-160 (January 2006) DOI: 10.1038/sj.jid.5700026 Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Hematoxylin-and-eosin-stained sections (panels a and c) with respective immunohistochemistry for Pten (panels b and d), showing intact staining for Pten (panel b) and virtually a complete loss of Pten (panel d) in the same fields of the two cases, respectively. Endothelial cells in vessels serve as the internal positive control. Journal of Investigative Dermatology 2006 126, 154-160DOI: (10.1038/sj.jid.5700026) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions