T. Iirola, S. Vilo, R. Aantaa, M. Wendelin-Saarenhovi, P. J

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Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers T. Iirola, S. Vilo, R. Aantaa, M. Wendelin-Saarenhovi, P.J. Neuvonen, M. Scheinin, K.T. Olkkola British Journal of Anaesthesia Volume 106, Issue 4, Pages 522-527 (April 2011) DOI: 10.1093/bja/aer004 Copyright © 2011 The Author(s) Terms and Conditions

Fig 1 Plasma concentrations of paracetamol [median (range)] in 12 healthy male volunteers after ingestion of 1 g of paracetamol and 10 g of lactulose after i.v. infusions of saline placebo, dexmedetomidine, or morphine. British Journal of Anaesthesia 2011 106, 522-527DOI: (10.1093/bja/aer004) Copyright © 2011 The Author(s) Terms and Conditions

Fig 2 Individual values for time to peak plasma paracetamol concentration (Tmax), peak plasma paracetamol concentration (Cmax), area under the paracetamol plasma concentration–time curve from 0 to 90 min (AUC0–90 min), and oro-caecal transit time measured by hydrogen breath test in 12 healthy male volunteers after ingestion of 1 g of paracetamol and 10 g of lactulose after i.v. infusion of saline placebo, dexmedetomidine or morphine. Dexmed, dexmedetomidine. British Journal of Anaesthesia 2011 106, 522-527DOI: (10.1093/bja/aer004) Copyright © 2011 The Author(s) Terms and Conditions