Effect of endovascular and open abdominal aortic aneurysm repair on thrombin generation and fibrinolysis Mohamed F. Abdelhamid, MBBCH (Hon), MSc, MRCSEd,

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Presentation transcript:

Effect of endovascular and open abdominal aortic aneurysm repair on thrombin generation and fibrinolysis Mohamed F. Abdelhamid, MBBCH (Hon), MSc, MRCSEd, Robert S.M. Davies, MRCS, Rajiv K. Vohra, MD, FRCS, Donald J. Adam, MD, FRCSEd, Andrew W. Bradbury, BSc, MBA, MD, FRCSEd Journal of Vascular Surgery Volume 57, Issue 1, Pages 103-107 (January 2013) DOI: 10.1016/j.jvs.2012.07.024 Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 1 The horizontal lines represent the normal range according to the manufacturer's guidance. A, Prothrombin fragment (PF)1 + 2. The preoperative group is significantly higher than the other groups. B, Thrombin-antithrombin (TAT) complex. There is no significant difference between the four groups. AMC, Age-matched control; EVAR, endovascular aneurysm repair; OAR, open aortic repair. Journal of Vascular Surgery 2013 57, 103-107DOI: (10.1016/j.jvs.2012.07.024) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 2 A, Plasminogen activator inhibitor (PAI) activity, 12 months post-open aortic repair (OAR) is significantly higher than in the preoperative group. B, The tissue-plasminogen activator (t-PA) antigen. There is no significant difference between the four groups. AMC, Age-matched control; EVAR, endovascular aneurysm repair. Journal of Vascular Surgery 2013 57, 103-107DOI: (10.1016/j.jvs.2012.07.024) Copyright © 2013 Society for Vascular Surgery Terms and Conditions