Volume 146, Issue 7, Pages e1 (June 2014)

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Volume 146, Issue 7, Pages 1680-1690.e1 (June 2014) Nonselective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients With Cirrhosis and Spontaneous Bacterial Peritonitis Mattias Mandorfer, Simona Bota, Philipp Schwabl, Theresa Bucsics, Nikolaus Pfisterer, Matthias Kruzik, Michael Hagmann, Alexander Blacky, Arnulf Ferlitsch, Wolfgang Sieghart, Michael Trauner, Markus Peck-Radosavljevic, Thomas Reiberger Gastroenterology Volume 146, Issue 7, Pages 1680-1690.e1 (June 2014) DOI: 10.1053/j.gastro.2014.03.005 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 Effect of NSBB treatment on (A) systolic arterial pressure (SAP), (B) mean arterial pressure (MAP) and the proportion of hemodynamically comprised patients with (C) SAP <100 mmHg and (D) MAP <82 mmHg at the time of the first paracentesis and the first SBP development. Gastroenterology 2014 146, 1680-1690.e1DOI: (10.1053/j.gastro.2014.03.005) Copyright © 2014 AGA Institute Terms and Conditions

Figure 2 Impact of NSBB treatment on transplant-free survival according to SBP status. Patients without SBP at first diagnosis started in (A) (no-SBP), while Patients with SBP at the first paracentesis started in (B) (SBP). At the first SBP diagnosis, patients were censored in (A) (no-SBP), entered (B) (SBP), and remained in this group. Gastroenterology 2014 146, 1680-1690.e1DOI: (10.1053/j.gastro.2014.03.005) Copyright © 2014 AGA Institute Terms and Conditions

Figure 3 Influence of NSBB treatment on transplant-free survival after the first SBP diagnosis. Gastroenterology 2014 146, 1680-1690.e1DOI: (10.1053/j.gastro.2014.03.005) Copyright © 2014 AGA Institute Terms and Conditions

Figure 4 Influence of NSBB treatment on HRS and grade C AKI development within 90 days after the first SBP diagnosis. Gastroenterology 2014 146, 1680-1690.e1DOI: (10.1053/j.gastro.2014.03.005) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 1 Influence of NSBB treatment on SBP incidence. Gastroenterology 2014 146, 1680-1690.e1DOI: (10.1053/j.gastro.2014.03.005) Copyright © 2014 AGA Institute Terms and Conditions