Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively.

Slides:



Advertisements
Similar presentations
Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study  J.J. Stefanik,
Advertisements

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.
The role of imaging modalities in the diagnosis, differential diagnosis and clinical assessment of peripheral joint osteoarthritis  C.Y.J. Wenham, A.J.
Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS)  F.W. Roemer, A. Guermazi, S.
Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from.
Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative  M. Hakky, M. Jarraya,
T1ρ relaxation time of the meniscus and its relationship with T1ρ of adjacent cartilage in knees with acute ACL injuries at 3T  R.I. Bolbos, Ph.D., T.M.
Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study  F.W. Roemer, T. Neogi,
Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study  J.J. Stefanik,
Imaging following acute knee trauma
Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.
Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis.
Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort  W. Wirth, M.S., M.-P. Hellio.
Imaging of non-osteochondral tissues in osteoarthritis
7th International Workshop on Osteoarthritis Imaging report: “imaging in OA – now is the time to move ahead”  A. Guermazi, F. Eckstein, D. Hunter, F.
H. A. Kim, I. Kim, Y. W. Song, D. H. Kim, J. Niu, A. Guermazi, M. D
Osteoarthritis as a disease of mechanics
Peripatellar synovitis: comparison between non-contrast-enhanced and contrast- enhanced MRI and association with pain. The MOST study  M.D. Crema, D.T.
Reference values and Z-scores for subregional femorotibial cartilage thickness – results from a large population-based sample (Framingham) and comparison.
Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study  A. Guermazi,
Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score)  D.J. Hunter, A. Guermazi, G.H. Lo, A.J. Grainger,
The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from.
Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritis  S. Amin,
Morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee  S.H. Hwang, K.A. Jung, W.J. Lee, K.H. Yang,
Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss  M.
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative 
Structural correlates of pain in joints with osteoarthritis
L. A. MacFarlane, H. Yang, J. E. Collins, A. Guermazi, M. H. Jones, E
Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.
Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic.
Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.
Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative 
Risk factors for meniscal body extrusion on MRI in subjects free of radiographic knee osteoarthritis: longitudinal data from the Osteoarthritis Initiative 
The impact of knee instability with and without buckling on balance confidence, fear of falling and physical function: the Multicenter Osteoarthritis.
Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS)  F.W. Roemer, A. Guermazi, S.
S. Reichenbach, M. D. , A. Guermazi, M. D. , J. Niu, M. B. B. S. , D
Comparison between semiquantitative and quantitative methods for the assessment of knee synovitis in osteoarthritis using non-enhanced and gadolinium-enhanced.
M. K. Javaid, J. A. Lynch, I. Tolstykh, A. Guermazi, F. Roemer, P
Associations between magnetic resonance imaging-defined structural pathologies and generalized and localized knee pain – the Oulu Knee Osteoarthritis.
Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial  M. Henriksen, D.J.
M. Wang, A. Radjenovic, T. W. Stapleton, R. Venkatesh, S. Williams, E
D. Hayashi, F.W. Roemer, A. Guermazi  Osteoarthritis and Cartilage 
Pre-radiographic osteoarthritic changes are highly prevalent in the medial patella and medial posterior femur in older persons: Framingham OA study  D.
The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period  M.D. Crema, A.
Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.
Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative  W. Wirth, J. Duryea,
Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative  S. Maschek,
N. Segal, E. Frick, M. Nevitt, J. Torner, D. Felson, A. Guermazi, D
Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:
F.W. Roemer, M.D.  Osteoarthritis and Cartilage 
How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative  F.
Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.
Comparison of BLOKS and WORMS scoring systems part I
Assessment of clinical and MRI outcomes after mesenchymal stem cell implantation in patients with knee osteoarthritis: a prospective study  Y.S. Kim,
Spectrum of meniscal pathology in osteoarthritis revisited - from signal change to complete destruction.  M. Jarraya, F.W. Roemer, M. Englund, M.D. Crema,
Cartilage thickness loss and clinical worsening are associated in osteoarthritic knees reaching virtual replacement status – A nested case control study.
Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study  D.K. White, C. Tudor-Locke, Y.
Synovitis and the risk of knee osteoarthritis: the MOST Study
Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal.
Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.
Trajectory of cartilage loss within 4 years of knee replacement – a nested case–control study from the Osteoarthritis Initiative  F. Eckstein, R.M. Boudreau,
The association between meniscal damage of the posterior horns and posterior localized synovitis detected on T1-weighted contrast-enhanced MRI: the most.
Susceptibility artifacts detected on 3T MRI of the knee: frequency, change over time and associations with radiographic findings: data from the Joints.
Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study  M.D. Crema, D.T. Felson, A. Guermazi,
CT imaging for evaluation of calcium crystal deposition in the knee: initial experience from the Multicenter Osteoarthritis (MOST) study  D. Misra, A.
The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies 
Abnormalities identified in the knees of asymptomatic volunteers using peripheral magnetic resonance imaging  K.A. Beattie, B.Sc., P. Boulos, M.D., F.R.C.P.
Osteoarthritis year 2012 in review: imaging
Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative  K. Bloecker,
Fig. 1. Right knee MRI of a 44-year-old male presenting with knee pain previously treated at an outside hospital. (a) Coronal fat-saturated T2 weighted.
Presentation transcript:

Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively defined cartilage thickness loss in knee osteoarthritis: the Multicenter Osteoarthritis Study  A. Guermazi, F. Eckstein, D. Hayashi, F.W. Roemer, W. Wirth, T. Yang, J. Niu, L. Sharma, M.C. Nevitt, C.E. Lewis, J. Torner, D.T. Felson  Osteoarthritis and Cartilage  Volume 23, Issue 12, Pages 2191-2198 (December 2015) DOI: 10.1016/j.joca.2015.06.017 Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Flowchart summarizing the subject inclusion/exclusion process. Osteoarthritis and Cartilage 2015 23, 2191-2198DOI: (10.1016/j.joca.2015.06.017) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Sagittal proton density-weighted fat suppressed MRI shows (a) a parrot-beak tear of the posterior horn of the medial meniscus reaching the inferior surface of the meniscus (arrow). This lesion would be scored as a grade 1 lesion in WORMS; (b) a non-displaced horizontal-oblique tear of the posterior horn of the medial meniscus reaching both, the superior and inferior surfaces of the meniscus (arrows). This tear type would be assessed as a grade 2 lesion in WORMS. Coronal STIR MRI shows (c) partial maceration (i.e., substance loss) of the meniscal body with an amputated triangular appearance (arrow). This finding represents a grade 3 lesion in the WORMS system; (d) complete maceration or substance loss of the lateral meniscal body. No meniscus is seen in the weight-bearing central subregions of the LFTC (arrows). This finding represents a grade 4 lesion in WORMS. Osteoarthritis and Cartilage 2015 23, 2191-2198DOI: (10.1016/j.joca.2015.06.017) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions