A Novel Cytidine Deaminase Affects Antibody Diversity

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A Novel Cytidine Deaminase Affects Antibody Diversity Angelika Longacre, Ursula Storb Cell Volume 102, Issue 5, Pages 541-544 (September 2000) DOI: 10.1016/S0092-8674(00)00075-1

Figure 1 Ig Gene Class Switch Recombination Example of switching from Cμ to Cε. S, switch region; the flags indicate transcription promoters. Cell 2000 102, 541-544DOI: (10.1016/S0092-8674(00)00075-1)

Figure 2 Distribution of Mutations in Somatic Hypermutation of Ig Genes Cell 2000 102, 541-544DOI: (10.1016/S0092-8674(00)00075-1)

Figure 3 Model of Somatic Hypermutation of Ig Genes E, Ig enhancer; IEB, Ig enhancer binding proteins; MuF, mutator factor; pol, RNA polymerase; Fen1, flap endonuclease 1; x, mutation. Cell 2000 102, 541-544DOI: (10.1016/S0092-8674(00)00075-1)