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Volume 7, Issue 3, Pages 353-360 (March 2010) Differences in effects of electrical therapy type for ventricular arrhythmias on mortality in implantable cardioverter-defibrillator patients Michael O. Sweeney, MD, Lou Sherfesee, PhD, Paul J. DeGroot, MS, Mark S. Wathen, MD, Bruce L. Wilkoff, MD, FHRS Heart Rhythm Volume 7, Issue 3, Pages 353-360 (March 2010) DOI: 10.1016/j.hrthm.2009.11.027 Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 1 Distribution of therapy types applied to VT, FVT, and VF. Heart Rhythm 2010 7, 353-360DOI: (10.1016/j.hrthm.2009.11.027) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 2 Survival rates by rhythm and therapy type. Survival among patients treated only with ATP was identical to that in patients with no VT, whereas survival among patients who received shocks was significantly worse. The three patient groups were similar with respect to baseline predictors of mortality, which is consistent with the modeling results. Heart Rhythm 2010 7, 353-360DOI: (10.1016/j.hrthm.2009.11.027) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 3 Progression of arrhythmia burden by appropriate shock groups. Patients are partitioned by number of appropriate shocked episodes over follow-up (horizontal axis) and corresponding annualized rate of VA by episode type and therapy applied (vertical axis). Left panel: Increasing annualized rates of all VA types with increasing shock burden. Right panel: Increasing annualized rates of all VA and therapy types with increasing shock burden. Heart Rhythm 2010 7, 353-360DOI: (10.1016/j.hrthm.2009.11.027) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 4 Ventricular episodes and therapy types by survival status. VA episodes per patient month, segregated by type and therapy applied, are displayed among subjects who died compared with survivors. The monthly burden of all VA episode + therapy type combinations is higher among patients who died. Heart Rhythm 2010 7, 353-360DOI: (10.1016/j.hrthm.2009.11.027) Copyright © 2010 Heart Rhythm Society Terms and Conditions