The Pituitary Gland in the Laurence-Moon Syndrome MICHAEL D. WHITAKER, M.D.  Mayo Clinic Proceedings  Volume 62, Issue 3, Pages 216-222 (March 1987) DOI: 10.1016/S0025-6196(12)62445-8 Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Histologic sections from anterior pituitary, demonstrating normal cellular morphologic features (A) and normal cellular densities of lactotropic (B), somatotropic (C), and corticotropic (D) cells. (A, Hematoxylin-eosin; x250. B-D, Avidin-biotin-peroxidase technique; x250.) Histologic sections from anterior pituitary, demonstrating normal cellular densities of gonadotropic cells elaborating luteinizing hormone (E) and follicle-stimulating hormone (F), thyrotropic cells (G), and α-subunit-producing glycoprotein cells (H). (E-H, Avidin-biotin-peroxidase technique; x250.) Mayo Clinic Proceedings 1987 62, 216-222DOI: (10.1016/S0025-6196(12)62445-8) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Histologic sections from anterior pituitary, demonstrating normal cellular morphologic features (A) and normal cellular densities of lactotropic (B), somatotropic (C), and corticotropic (D) cells. (A, Hematoxylin-eosin; x250. B-D, Avidin-biotin-peroxidase technique; x250.) Histologic sections from anterior pituitary, demonstrating normal cellular densities of gonadotropic cells elaborating luteinizing hormone (E) and follicle-stimulating hormone (F), thyrotropic cells (G), and α-subunit-producing glycoprotein cells (H). (E-H, Avidin-biotin-peroxidase technique; x250.) Mayo Clinic Proceedings 1987 62, 216-222DOI: (10.1016/S0025-6196(12)62445-8) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 A, Testicular tissue, demonstrating spermatogenesis and mild reduction in interstitial cells. (Hematoxylin-eosin; xl60.) B, Breast tissue, showing gynecomastia characterized by ductal proliferation and stromal fibrosis. (Hematoxylin-eosin; x100.) Mayo Clinic Proceedings 1987 62, 216-222DOI: (10.1016/S0025-6196(12)62445-8) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 A, Retinal pigment epithelium (arrows), showing flattening and paucity of pigment granules. Adjacent photoreceptors are atrophic. (Hematoxylin-eosin; x400.) B, Extraocular muscle, demonstrating diffuse atrophy of muscle fibers; many show central nuclei. (Hematoxylin-eosin; x250.) Mayo Clinic Proceedings 1987 62, 216-222DOI: (10.1016/S0025-6196(12)62445-8) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions