Attention Deficit Hyperactivity Disorder: Fine Mapping Supports Linkage to 5p13, 6q12, 16p13, and 17p11 Matthew N. Ogdie, Simon E. Fisher, May Yang,

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Attention Deficit Hyperactivity Disorder: Fine Mapping Supports Linkage to 5p13, 6q12, 16p13, and 17p11 Matthew N. Ogdie, Simon E. Fisher, May Yang, Janeen Ishii, Clyde Francks, Sandra K. Loo, Rita M. Cantor, James T. McCracken, James J. McGough, Susan L. Smalley, Stanley F. Nelson The American Journal of Human Genetics Volume 75, Issue 4, Pages 661-668 (October 2004) DOI: 10.1086/424387 Copyright © 2004 The American Society of Human Genetics Terms and Conditions

Figure 1 Multipoint MLS values for nine candidate regions in 308 ASPs with ADHD. The X-axis values are distances from the p-telomere, in Kosambi cM. The MLS values for the 10-cM genomewide scan of 270 ASPs (Ogdie et al. 2003) are shown in red. The fine-mapping values, at ∼ 2-cM marker density in candidate regions, are shown in blue. The blue bar indicates the approximate fine-mapping interval. The identical MLS values for the 2-cM and 10-cM analyses for chromosomes 7 and 9 and a large portion of chromosome 15 give the appearance of a single line. MLS analysis was performed by ASPEX sib_ibd, under the possible triangle. The American Journal of Human Genetics 2004 75, 661-668DOI: (10.1086/424387) Copyright © 2004 The American Society of Human Genetics Terms and Conditions