Patterns of statin use and cholesterol goal attainment in a high-risk cardiovascular population: A retrospective study of primary care electronic medical.

Slides:



Advertisements
Similar presentations
Corn oil improves the plasma lipoprotein lipid profile compared with extra-virgin olive oil consumption in men and women with elevated cholesterol: Results.
Advertisements

Hypertension-Lipid Connection: Introduction
A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality  Rishi K. Wadhera,
Lipid abnormalities in foreign-born and US-born patients in a medical group  Jawali Jaranilla, MD, MPH, Terese DeFor, MS, Gabriela Vazquez Benitez, PhD,
Patient and Physician Perspectives on Administration of the PCSK9 Monoclonal Antibody Alirocumab, an Injectable Medication to Lower LDL-C Levels†  Eli.
A randomized trial evaluating the efficacy and safety of alirocumab in South Korea and Taiwan (ODYSSEY KT)  Kwang Kon Koh, MD, PhD, FACC, Chang Wook Nam,
The UK Paediatric Familial Hypercholesterolaemia Register: Statin-related safety and 1- year growth data  Steve E. Humphries, PhD, FRCP, Jackie Cooper,
Long-term Medical Management of the Liver Transplant Recipient: What the Primary Care Physician Needs to Know  Siddharth Singh, MD, Kymberly D. Watt,
Charles R. Harper, MD, Terry A. Jacobson, MD  Mayo Clinic Proceedings 
2013 Cholesterol Guidelines Revisited: Percent LDL Cholesterol Reduction or Attained LDL Cholesterol Level or Both for Prognosis?  Sripal Bangalore, MD,
Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident cardiovascular disease: The Framingham Heart.
Corn oil improves the plasma lipoprotein lipid profile compared with extra-virgin olive oil consumption in men and women with elevated cholesterol: Results.
Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 monoclonal antibody alirocumab vs placebo in patients with heterozygous familial.
An assessment by the Statin Muscle Safety Task Force: 2014 update
An assessment by the Statin Liver Safety Task Force: 2014 update
Purified palmitoleic acid for the reduction of high-sensitivity C-reactive protein and serum lipids: A double-blinded, randomized, placebo controlled.
Martin W. Schoen, MD, MPH, Joanne Salas, MPH, Jeffrey F
Charles R. Harper, MD, Terry A. Jacobson, MD  Mayo Clinic Proceedings 
Efficacy and safety of gemcabene as add-on to stable statin therapy in hypercholesterolemic patients  Evan Stein, MD, Harold Bays, MD, Michael Koren,
Association of triglyceride-to-high density lipoprotein cholesterol ratio to cardiorespiratory fitness in men  Gloria Lena Vega, PhD, Scott M. Grundy,
KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update
Emerging LDL therapies: Mipomersen—antisense oligonucleotide therapy in the management of hypercholesterolemia  Peter P. Toth, MD, PhD, FAAFP, FICA, FNLA,
Omega-3 carboxylic acids in patients with severe hypertriglyceridemia: EVOLVE II, a randomized, placebo-controlled trial  Erik S.G. Stroes, MD, PhD, Andrey.
Glucagon-like peptide-1 receptor agonists reduced the low-density lipoprotein cholesterol in Japanese patients with type 2 diabetes mellitus treated with.
A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality  Rishi K. Wadhera,
Apolipoprotein E-containing high-density lipoprotein (HDL) modifies the impact of cholesterol-overloaded HDL on incident coronary heart disease risk:
Predictors of first-year statin medication discontinuation: A cohort study  Heli Halava, MD, Risto Huupponen, MD, PhD, Jaana Pentti, BSc, Mika Kivimäki,
Efficacy of alirocumab in 1191 patients with a wide spectrum of mutations in genes causative for familial hypercholesterolemia  Joep C. Defesche, PhD,
Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study  Tim Christen, MSc, Stella.
The UK Paediatric Familial Hypercholesterolaemia Register: Statin-related safety and 1- year growth data  Steve E. Humphries, PhD, FRCP, Jackie Cooper,
Effects of icosapent ethyl on lipoprotein particle concentration and size in statin-treated patients with persistent high triglycerides (the ANCHOR Study) 
Lipid and lipoprotein reference values from 133,450 Dutch Lifelines participants: Age- and gender-specific baseline lipid values and percentiles  Jan.
A 3-year study of atorvastatin in children and adolescents with heterozygous familial hypercholesterolemia  Gisle Langslet, MD, Andrei Breazna, PhD, Euridiki.
Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance 
Jonathan C. Cohen, PhD  Journal of Clinical Lipidology 
J. W. Balder, MD, PhD, P. J. Lansberg, MD, PhD, M. H. Hof, MSc, A
Efficacy and safety of alirocumab, a monoclonal antibody to PCSK9, in statin-intolerant patients: Design and rationale of ODYSSEY ALTERNATIVE, a randomized.
Meredith Kilgore, PhD, Paul Muntner, PhD, J
Non–high-density lipoprotein cholesterol target achievement in patients on lipid-lowering drugs and stratified by triglyceride levels in the Arabian Gulf 
Emma J. Aarnio, MSc (Pharm), Janne A
Lysosomal acid lipase deficiency: A hidden disease among cohorts of familial hypercholesterolemia?  Joana Rita Chora, MSc, Ana Catarina Alves, PhD, Ana.
Charles J. Glueck, MD, Alan Brown, MD, Anne C. Goldberg, MD, James M
Paul D. Thompson, MD, John Rubino, MD, Matthew J. Janik, MD, Diane E
Effects of exercise rehabilitation on cardiovascular risk factors in older patients with peripheral arterial occlusive disease  Anna Maria Izquierdo-Porrera,
Increased prevalence of clinical and subclinical atherosclerosis in patients with damaging mutations in ABCA1 or APOA1  Omar Abdel-Razek, MD, Singh N.
Barriers to PCSK9 inhibitor prescriptions for patients with high cardiovascular risk: Results of a healthcare provider survey conducted by the National.
An assessment by the Statin Intolerance Panel: 2014 update
Task-sharing interventions for cardiovascular risk reduction and lipid outcomes in low- and middle-income countries: A systematic review and meta-analysis 
Assessment of statin therapy, LDL-C levels, and cardiovascular events among high-risk patients in the United States  Sudhir K. Unni, PhD, MBA, Ruben G.W.
Long-term treatment adherence to the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab in 6 ODYSSEY Phase III clinical studies with treatment.
Lipid and lipoprotein reference values from 133,450 Dutch Lifelines participants: Age- and gender-specific baseline lipid values and percentiles  Jan.
Corn oil improves the plasma lipoprotein lipid profile compared with extra-virgin olive oil consumption in men and women with elevated cholesterol: Results.
Xing Wu, MD, PhD, Zhexin Yu, MD, MS, Wen Su, MD, PhD, Daniel A
Optimal high-density lipoprotein cholesterol cutoff for predicting cardiovascular disease: Comparison of the Korean and US National Health and Nutrition.
Alirocumab efficacy in patients with double heterozygous, compound heterozygous, or homozygous familial hypercholesterolemia  Merel L. Hartgers, MD, Joep.
Sokunthea Peou, PharmD, Brittany Milliard-Hasting, MD, Sachin A
Familial hypercholesterolemia in a European Mediterranean population—Prevalence and clinical data from 2.5 million primary care patients  Alberto Zamora,
Influence of low-glucose peritoneal dialysis on serum lipids and apolipoproteins in the IMPENDIA/EDEN trials  Allan D. Sniderman, MD, James A. Sloand,
Rhanderson Cardoso, MD, Roger S
Diabetes is associated with an increased risk of cardiovascular disease in patients with familial hypercholesterolemia  Martine Paquette, MSc, Sophie.
Efficacy and safety of lipoprotein apheresis in children with homozygous familial hypercholesterolemia: A systematic review  Ilse K. Luirink, MD, Jim.
Alirocumab efficacy in patients with double heterozygous, compound heterozygous, or homozygous familial hypercholesterolemia  Merel L. Hartgers, MD, Joep.
Higher long-term adherence to statins in rural patients at high atherosclerotic risk  Matthew R. Peverelle, MD, BBiomed, Arul Baradi, MBChB, Sarang Paleri,
Individualized low-density lipoprotein cholesterol reduction with alirocumab titration strategy in heterozygous familial hypercholesterolemia: Results.
Can Low-Radiation Coronary Computed Tomography Angiography Improve Upon Clinical Risk Assessment in Patients with Familial Hypercholesterolemia?*  Anna.
Urbanization, mainly rurality, but not altitude is associated with dyslipidemia profiles  Maria Lazo-Porras, Antonio Bernabe-Ortiz, Renato Quispe, German.
Prediction of Cardiovascular Disease Events by Lipoprotein(a) According to LDL-C in Older High Risk Adults  Nathan D. Wong, PhD, Shravanthi R. Gandra,
Emerging low-density lipoprotein (LDL) therapies: Management of severely elevated LDL cholesterol—The role of LDL-apheresis  Mary P. McGowan, MD, FNLA 
Long-term clinical results of microsomal triglyceride transfer protein inhibitor use in a patient with homozygous familial hypercholesterolemia  Anna.
National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1 – executive summary  Terry A. Jacobson, MD, Matthew.
Presentation transcript:

Patterns of statin use and cholesterol goal attainment in a high-risk cardiovascular population: A retrospective study of primary care electronic medical records  Maria García-Gil, MD, PhD, Jordi Blanch, MSc, Marc Comas-Cufí, MSc, Josep Daunis-i-Estadella, PhD, Bonaventura Bolíbar, MD, Ruth Martí, PhD, Anna Ponjoan, PhD, Lia Alves-Cabratosa, MD, Rafel Ramos, MD, PhD  Journal of Clinical Lipidology  Volume 10, Issue 1, Pages 134-142 (January 2016) DOI: 10.1016/j.jacl.2015.10.007 Copyright © 2016 National Lipid Association Terms and Conditions

Figure 1 Probability of low-density lipoprotein cholesterol (LDL-C) goal attainment (A: LDL-C < 3.36 mmol/L and B: LDL-C < 2.59 mmol/L) according to patterns of statin use and MPR. MPR, Medical Possession Ratio; OR, ddds ratio. Journal of Clinical Lipidology 2016 10, 134-142DOI: (10.1016/j.jacl.2015.10.007) Copyright © 2016 National Lipid Association Terms and Conditions