Association between statin use and consultation or surgery for osteoarthritis of the hip or knee: a pooled analysis of four cohort studies K. Michaëlsson,

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Presentation transcript:

Association between statin use and consultation or surgery for osteoarthritis of the hip or knee: a pooled analysis of four cohort studies K. Michaëlsson, L.S. Lohmander, A. Turkiewicz, A. Wolk, P. Nilsson, M. Englund Osteoarthritis and Cartilage Volume 25, Issue 11, Pages 1804-1813 (November 2017) DOI: 10.1016/j.joca.2017.07.013 Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Forest plots displaying the association between current statin use compared with never use for the multivariable adjusted HRs of consultation or surgery for OA of the hip or knee. Panel A shows results for non-surgically and surgically treated OA, panel B shows the same outcome but with the analysis restricted to patients using antihypertensives, panel C shows the results for the outcome surgically treated OA without any restriction in the databases, and panel D shows the results for the outcome surgically treated OA restricted to an analysis of patients using antihypertensives. Osteoarthritis and Cartilage 2017 25, 1804-1813DOI: (10.1016/j.joca.2017.07.013) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Forest plots displaying HRs of consultation or surgery for OA of the hip or knee by former use and by categories of duration of use in current statin users, with never users of statin as the reference. Osteoarthritis and Cartilage 2017 25, 1804-1813DOI: (10.1016/j.joca.2017.07.013) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Forest plots displaying HRs of consultation or surgery for OA of the hip or knee by low, medium and high dose of current statin use, with never users of statin as the reference. Panel A shows results without cohort restriction and panel B shows results in users of antihypertensives. Osteoarthritis and Cartilage 2017 25, 1804-1813DOI: (10.1016/j.joca.2017.07.013) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions