C. Oprica, C.E. Nord Clinical Microbiology and Infection

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European surveillance study on the antibiotic susceptibility of Propionibacterium acnes C. Oprica, C.E. Nord Clinical Microbiology and Infection Volume 11, Issue 3, Pages 204-213 (March 2005) DOI: 10.1111/j.1469-0691.2004.01055.x Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 (a) Clindamycin MICs for the isolates resistant to both clindamycin and erythromycin; MIC range = 0.25–64 mg/L, 73% of strains have MIC ≥ 2 mg/L. (b) Erythromycin MICs for the isolates resistant to both clindamycin and erythromycin; MIC range = 0.5–128 mg/L, 84% of strains have MIC ≥ 2 mg/L. (c) Clindamycin MICs for the clindamycin-resistant isolates; MIC range = 0.25–2 mg/L, 3% of strains have MIC ≥ 2 mg/L. (d) Erythromycin MICs for the erythromycin-resistant isolates; MIC range = 0.5–128 mg/L, 11% of strains have MIC ≥ 2 mg/L. Clinical Microbiology and Infection 2005 11, 204-213DOI: (10.1111/j.1469-0691.2004.01055.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Correlation between the reported sales of macrolides/lincosamides (MLS) in eight EU countries and the resistance rates to (a) clindamycin, and (b) erythromycin in these countries. By linear regression analysis, the clindamycin and erythromycin resistance rates correlate with the reported sales of MLS (1.4998 + 0.12846 × clindamycin resistance rates, p < 0.05, r = 0.753; and 1.6551 + 0.07345 × erythromycin resistance rates, p < 0.05, r = 0.713, respectively). Solid lines show mean values; dashed lines show 95% confidence intervals. Clinical Microbiology and Infection 2005 11, 204-213DOI: (10.1111/j.1469-0691.2004.01055.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Distribution of six resistant phenotypes among 17 clones identified by pulsed-field gel electrophoresis. CL, clindamycin; EM, erythromycin; TCY, tetracycline. Clinical Microbiology and Infection 2005 11, 204-213DOI: (10.1111/j.1469-0691.2004.01055.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions