How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative F.

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Presentation transcript:

How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative F. Eckstein, C.E. Mc Culloch, J.A. Lynch, M. Nevitt, C.K. Kwoh, S. Maschek, M. Hudelmaier, L. Sharma, W. Wirth Osteoarthritis and Cartilage Volume 20, Issue 11, Pages 1250-1257 (November 2012) DOI: 10.1016/j.joca.2012.06.019 Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Bar graphs showing the magnitude of longitudinal change in cartilage thickness thickness in the total femorotibial joint (top) and in FTJ, in the central medial femorotibial (cMFTC) joint (bottom) (Δ ThCtAB in μm) over 1 year, 2 years, 3 years, and 4 years in knees with KLG 2 and 3, respectively. Changes between BL and Y1 follow-up and between Y1 and Y2 were averaged to compute the 1-year change, and changes between BL and Y2 and between Y2 and Y4 were averaged to compute the 2-year change. Changes between Y1 and Y4 were used to compute the 3-year (3Y) and those between BL and Y4 to compute the 4-year change (4Y). Osteoarthritis and Cartilage 2012 20, 1250-1257DOI: (10.1016/j.joca.2012.06.019) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Scatter plot showing the relationship between short term (Y1 → Y2) and longterm (BL → Y4) change in cartilage thickness (in μm) for Kellgren Lawrence grade (KLG) 2 and KLG3 knees, respectively: (top) in the total femorotibial joint (FTJ); (bottom) in the central medial femorotibial compartment (cMFTC). Osteoarthritis and Cartilage 2012 20, 1250-1257DOI: (10.1016/j.joca.2012.06.019) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions