Agenda 4/1 Pedigree Lecture Pedigree Practice Hemophilia Case Study Turn in: POGIL answers Homework 1. Finish Case Study 2. Hardy-Weinberg Practice

Is a widow’s peak a dominant or recessive trait? b) Key Male Female Affected male Affected female Mating Offspring 1st generation Ff Ff ff Ff 1st generation Ww ww ww Ww 2nd generation 2nd generation FF or Ff ff ff Ff Ff ff Ww ww ww Ww Ww ww 3rd generation 3rd generation ff FF or Ff WW or Ww ww A valuable tool in studying inheritance patterns is a pedigree. A pedigree is a family tree that describes the interrelationships of parents and children across generations Inheritance patterns of particular traits can be traced and described using pedigrees Widow’s peak No widow’s peak Attached earlobe Free earlobe (a) Is a widow’s peak a dominant or recessive trait? b) Is an attached earlobe a dominant or recessive trait?

Pedigree Symbols

Pedigree #1

Pedigree #1

Pedigree #1

Pedigree #1 Characteristics of a dominant pedigree: 1) Every affected individual has at least one affected parent 2) Affected individuals who mate with unaffected individuals have a 50% chance of transmitting the trait to each child; and 3) Two affected individuals may have unaffected children.

Pedigree #2

Pedigree #2

Pedigree #2

Pedigree #2 Characteristics of recessive pedigrees: 1) An individual who is affected may have parents who are not affected 2) All the children of two affected individuals are affected 3) In pedigrees involving rare traits, the unaffected parents of an affected individual may be related to each other.

Pedigree #3

Pedigree #3

Pedigree #3

Pedigree #3 Characteristics of sex-linked pedigrees All females from the affected male have the trait, but not all males from affected females (dominant) All males from the affected female have the trait, but not all females from affected males (recessive)

Label the genotypes and identify type of inheritance