Aha, Another Regulator for Hsp90 Chaperones

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Aha, Another Regulator for Hsp90 Chaperones Matthias P Mayer, Rainer Nikolay, Bernd Bukau Molecular Cell Volume 10, Issue 6, Pages 1255-1256 (December 2002) DOI: 10.1016/S1097-2765(02)00793-1

Figure 1 Domain Structure of Hsp90 and Regulation of the Hsp90 Functional Cycle (A) Function of Hsp90 domains and interacting cofactors. If different, the names of yeast homologs are given in parentheses. (B) Hsp90 chaperone cycle of Hsp90 emphasizing the ATPase inhibitory (blue blunt arrows) and stimulatory (red arrows) effects of the cochaperones. “C” symbolizes client protiens. Molecular Cell 2002 10, 1255-1256DOI: (10.1016/S1097-2765(02)00793-1)