Residual and Progressive Aortic Regurgitation After Valve-Sparing Root Replacement: A Propensity-Matched Multi-Institutional Analysis in 764 Patients

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Residual and Progressive Aortic Regurgitation After Valve-Sparing Root Replacement: A Propensity-Matched Multi-Institutional Analysis in 764 Patients Fabian A. Kari, MD, Kai-Nicolas Doll, MD, Wolfgang Hemmer, MD, Markus Liebrich, MD, Hans-Hinrich Sievers, MD, Doreen Richardt, MD, Hermann Reichenspurner, MD, Christian Detter, MD, Matthias Siepe, MD, Martin Czerny, MD, Friedhelm Beyersdorf, MD The Annals of Thoracic Surgery Volume 101, Issue 4, Pages 1500-1506 (April 2016) DOI: 10.1016/j.athoracsur.2015.10.002 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Flow of patient selection process. (TTE = transthoracic echocardiography; V-SARR = valve-sparing aortic root replacement.) The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Absolute numbers of aortic valve replacement and yearly rates of combined endpoint progressive and new onset aortic regurgitation. The rates relate to number of patients actually available for follow-up in the respective year. The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Absolute numbers of aortic valve replacement and yearly rates of combined endpoint progressive and new onset aortic regurgitation, new onset aortic regurgitation only, and progressive aortic regurgitation only. The rates relate to number of patients actually available for follow-up in the respective year. The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Quintiles of propensity score levels. Score expresses propensity of being treated with an additional cusp repair. Variables used in the logistic regression with binary endpoint are listed in the graph. (AR = aortic regurgitation; NYHA = New York Heart Association; V-SARR = valve-sparing aortic root replacement.) The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Absolute numbers in different quintiles of treatment group and comparison group. The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Histograms showing distribution of aortic valve regurgitation grades at different time points. The Annals of Thoracic Surgery 2016 101, 1500-1506DOI: (10.1016/j.athoracsur.2015.10.002) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions