Value of a single preoperative PFA-100® measurement in assessing the risk of bleeding in patients taking cyclooxygenase inhibitors and undergoing total.

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Value of a single preoperative PFA-100® measurement in assessing the risk of bleeding in patients taking cyclooxygenase inhibitors and undergoing total knee replacement†  K.F.J. Ng, J.-C. Lawmin, S.F. Tsang, W.M. Tang, K.Y. Chiu  British Journal of Anaesthesia  Volume 102, Issue 6, Pages 779-784 (June 2009) DOI: 10.1093/bja/aep091 Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 1 Correlation of preoperative EPICT measured by the PFA-100®, with drain output in the first 24 h after operation (n=51, r=0.30, P=0.03). EPICT refers to PFA-100® closure times measured with epinephrine cartridge. British Journal of Anaesthesia 2009 102, 779-784DOI: (10.1093/bja/aep091) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 2 Correlation of preoperative (a) ADPCT (n=37) and (b) EPICT (n=35) with 20% haemodilution in vitro, measured using the PFA-100® with drain output in the first 24 h after operation. (a) r=0.35, P=0.04; (b) r=0.42, P=0.01. ADPCT and EPICT refer to PFA-100® closure times measured with adenosine-5'-diphosphate and epinephrine cartridges, respectively. British Journal of Anaesthesia 2009 102, 779-784DOI: (10.1093/bja/aep091) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

Fig 3 Receiver-operating characteristic (ROC) curve for predicting excessive drain output in the first 24 h after operation, using the preoperative EPICT with 20% haemodilution in vitro [area under the curve, 0.74 (95% CI 0.54–0.94)]. Excessive output is defined as output above the top 25% in this study, which is 270 ml. British Journal of Anaesthesia 2009 102, 779-784DOI: (10.1093/bja/aep091) Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

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