Genetic Factors and Hepatitis C Virus Infection

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Genetic Factors and Hepatitis C Virus Infection Alexander J. Thompson Gastroenterology Volume 142, Issue 6, Pages 1335-1339 (May 2012) DOI: 10.1053/j.gastro.2012.01.046 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 Proposed algorithm for the use of IL28B genotyping in the context of telaprevir/boceprevir regimens for treatment-naïve patients. ↑Data for caucasians13; *based on subanalyses of SPRINT-2/RESPOND-231 and ADVANCE29; **patients with advanced fibrosis/cirrhosis may be more suitable for DAA-based therapy; ***patients with advanced fibrosis/cirrhosis may not be suitable for treatment deferral. DAA = direct-acting antiviral; IFN, interferon; pegIFN, peginterferon-α; RBV, ribavirin; RGT, response-guided therapy. Gastroenterology 2012 142, 1335-1339DOI: (10.1053/j.gastro.2012.01.046) Copyright © 2012 AGA Institute Terms and Conditions

Gastroenterology 2012 142, 1335-1339DOI: (10. 1053/j. gastro. 2012. 01 Copyright © 2012 AGA Institute Terms and Conditions