Whole blood fatty acid analysis with micromethod in cystic fibrosis and pulmonary disease Patrizia Risé, Sonia Volpi, Claudio Colombo, Rita Francesca.

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Presentation transcript:

Whole blood fatty acid analysis with micromethod in cystic fibrosis and pulmonary disease Patrizia Risé, Sonia Volpi, Claudio Colombo, Rita Francesca Padoan, Ciro D'Orazio, Silvia Ghezzi, Paola Melotti, Veronica Bennato, Carlo Agostoni, Baroukh Maurice Assael, Claudio Galli Journal of Cystic Fibrosis Volume 9, Issue 3, Pages 228-233 (May 2010) DOI: 10.1016/j.jcf.2010.03.002 Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Δ6 desaturase (18:3 n-6/18:2 n-6) and Δ5 desaturase (20:4 n-6/20:3 n-6) activities, expressed as product/precursor ratios. Values are the mean±SE; significantly different from C at *: p<0.05. C, controls; CF, cystic fibrosis patients. Journal of Cystic Fibrosis 2010 9, 228-233DOI: (10.1016/j.jcf.2010.03.002) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 LA × DHA product assessed in whole blood, according to the severity of respiratory disease. A) Values are the mean±SE; significantly different from C at *: p<0.05. B) Values are median±interquartile range at 25 and 75 percentiles. Differences between FEV1% groups were determined by ANOVA analysis significant at p<0.05. C, controls; CF, cystic fibrosis patients; FEV1%, forced respiratory volume in 1s. Journal of Cystic Fibrosis 2010 9, 228-233DOI: (10.1016/j.jcf.2010.03.002) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions