Aortic valve replacement with the Mitroflow pericardial bioprosthesis: Durability results up to 21 years  Charles A. Yankah, MD, PhD, Miralem Pasic, MD,

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Aortic valve replacement with the Mitroflow pericardial bioprosthesis: Durability results up to 21 years  Charles A. Yankah, MD, PhD, Miralem Pasic, MD, PhD, Michele Musci, MD, Julia Stein, MSc, Christine Detschades, SRN, Henryk Siniawski, MD, PhD, Roland Hetzer, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 136, Issue 3, Pages 688-696 (September 2008) DOI: 10.1016/j.jtcvs.2008.05.022 Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Overall cumulative survival of all 1513 patients after aortic valve replacement and of a German population as background (data from Federal Bureau for Population Statistics, Wiesbaden, Germany). The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Actuarial freedom from reoperation for structural valve deterioration (SVD) in age groups (50–59, 60–69, and ≥70 years) after pericardial aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Actual (cumulative incidence) freedom from reoperation for structural valve deterioration (SVD) by age group (50–59, 60–69 and ≥70 years) after pericardial aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Actuarial and actual (cumulative incidence) freedom from reoperation for structural valve deterioration (SVD) in age group ≥65 years after pericardial aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Time-related transvalvular mean gradients in relation to labeled valve sizes. Each symbol represents a labeled valve size. Solid lines represent time-related estimates of median values for each prosthesis. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 6 Actuarial freedom from thromboembolism (TE) after pericardial aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

Figure 7 Hazard function of prosthetic valve endocarditis after pericardial aortic valve replacement. Constant hazard rate of events. The Journal of Thoracic and Cardiovascular Surgery 2008 136, 688-696DOI: (10.1016/j.jtcvs.2008.05.022) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions