C. E. Berger, M. D. , A. Kröner, M. D. , K. H. Kristen, M. D. , M

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Spontaneous osteonecrosis of the knee: biochemical markers of bone turnover and pathohistology C.E. Berger, M.D., A. Kröner, M.D., K.H. Kristen, M.D., M. Minai-Pour, M.D., T. Leitha, M.D., A. Engel, M.D. Osteoarthritis and Cartilage Volume 13, Issue 8, Pages 716-721 (August 2005) DOI: 10.1016/j.joca.2005.04.003 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 1 These graphs show the individual values of bone to serum ratios in patients with spontaneous ON (A) and OA (B) of the knee. (C) The graph shows the individual values of bone to serum ratios in healthy controls18. Osteoarthritis and Cartilage 2005 13, 716-721DOI: (10.1016/j.joca.2005.04.003) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 2 Photomicrograph of an osteonecrotic lesion (stain, Giemsa, original magnification, ×40). Rupture and collapse of the articular cartilage are seen adjacent to necrotic bone in the subchondral area (arrows). Necrotic bone marrow is surrounded by fibrovascular proliferation (granulation tissue). Osteoarthritis and Cartilage 2005 13, 716-721DOI: (10.1016/j.joca.2005.04.003) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions