Chapter 2: Neurons and conductance-based models

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Presentation transcript:

Chapter 2: Neurons and conductance-based models Fundamentals of Computational Neuroscience Chapter 2: Neurons and conductance-based models Dec 09

Biological background

Ion channels

Synapse

Non-NMDA: AMPA, GABA

Conductance-based models

MATLAB program

Hodgkin-Huxley model Typical form of an action potential; redrawn from an oscilloscope picture from Hodgkin and Huxley (1939). Alan Hodgkin and Andrew Huxley The Nobel Prize in Physiology or Medicine 1963 (with John Eccles)

The minimal mechanism

Hodgkin-Huxley equations and simulation

Compartmental models

Simulators

Further readings