M. F. Pustjens, S. C. Mastbergen, W. H. Noort-Van der Laan, R. J

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Presentation transcript:

The biochemical interaction between subchondral bone and cartilage in osteoarthritis M.F. Pustjens, S.C. Mastbergen, W.H. Noort-Van der Laan, R.J. Van Heerwaarden, F.P. Lafeber Osteoarthritis and Cartilage Volume 22, Pages S352-S353 (April 2014) DOI: 10.1016/j.joca.2014.02.652 Copyright © 2014 Terms and Conditions

Figure 1 Biochemical effects of bone on cartilage. Human knee subchondral osteoblasts were isolated form healthy donors (n=14) and OA patients (n=16). Osteoblast culture supernatants were subsequently tested on both healthy and osteoarthritic cartilage and changes in proteoglycan (PG) synthesis were studied (mean % change are given). Osteoarthritis and Cartilage 2014 22, S352-S353DOI: (10.1016/j.joca.2014.02.652) Copyright © 2014 Terms and Conditions