Localization of putative cholesterol-binding motifs in the homology model of human glucose transporter 1 (GLUT1) protein. Localization of putative cholesterol-binding.

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Localization of putative cholesterol-binding motifs in the homology model of human glucose transporter 1 (GLUT1) protein. Localization of putative cholesterol-binding motifs in the homology model of human glucose transporter 1 (GLUT1) protein. (A) A homology model of human GLUT1 protein: N-termini and C-termini are indicated and the placement within the plasma membrane is only schematic. (B). Putative cholesterol recognition/interaction amino acid consensus (CRAC)-like motifs in GLUT1: aa 83–89 (VGLFVNR, left) and aa 322–330 (VVSLFVVER, right). Dominika Nowis et al. BMJ Open Diab Res Care 2014;2:e000017 ©2014 by American Diabetes Association