The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial N.K. Arden, S. Cro, S. Sheard, C.J. Doré,

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The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial N.K. Arden, S. Cro, S. Sheard, C.J. Doré, A. Bara, S.A. Tebbs, D.J. Hunter, S. James, C. Cooper, T.W. O'Neill, A. Macgregor, F. Birrell, R. Keen Osteoarthritis and Cartilage Volume 24, Issue 11, Pages 1858-1866 (November 2016) DOI: 10.1016/j.joca.2016.05.020 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Consort flow diagram for the VIDEO study. Osteoarthritis and Cartilage 2016 24, 1858-1866DOI: (10.1016/j.joca.2016.05.020) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Mean JSW in the medial compartment of the index knee with 95% CI's by treatment group (N = 474). All available readings were included in primary analysis and multiple imputation was used to impute missing values, assuming all missing outcome values were missing at random, conditional on treatment and the covariates included in the imputation model. Both centre and baseline BMI were included in the imputation model. Osteoarthritis and Cartilage 2016 24, 1858-1866DOI: (10.1016/j.joca.2016.05.020) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Scatterplot of baseline vitamin D3 against estimated 3-year change in JSW by treatment group with linear fit imposed (N = 463). Osteoarthritis and Cartilage 2016 24, 1858-1866DOI: (10.1016/j.joca.2016.05.020) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions