Giancarlo Piano, MD, Bruce L. Gewertz, MD  Journal of Vascular Surgery 

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Presentation transcript:

Mechanism of increased cerebrospinal fluid pressure with thoracic aortic occlusion  Giancarlo Piano, MD, Bruce L. Gewertz, MD  Journal of Vascular Surgery  Volume 11, Issue 5, Pages 695-701 (May 1990) DOI: 10.1016/0741-5214(90)90216-W Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Aortic occlusion resulted in increased CVP, which was augmented by volume loading (*p < 0.05). Journal of Vascular Surgery 1990 11, 695-701DOI: (10.1016/0741-5214(90)90216-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 The increase in CSFP in response to thoracic aortic occlusion was greatest in volume loaded animals (*p < 0.05). Journal of Vascular Surgery 1990 11, 695-701DOI: (10.1016/0741-5214(90)90216-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 With aortic occlusion, the increase in CSFP (ΔP0) was equal to or greater than the increase in CVP (ΔCVP) (*p < 0.05). Journal of Vascular Surgery 1990 11, 695-701DOI: (10.1016/0741-5214(90)90216-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Compliance was not changed by aortic occlusion alone. Volume loading in group II was associated with an increase in compliance (*p < 0.05). Journal of Vascular Surgery 1990 11, 695-701DOI: (10.1016/0741-5214(90)90216-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Starling resistor model applied to spinal cord blood flow (see text). If CSFP exceeds local venous pressure, veins can collapse (arrows) thereby increasing outflow resistance. Journal of Vascular Surgery 1990 11, 695-701DOI: (10.1016/0741-5214(90)90216-W) Copyright © 1990 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions