A–E, Active avoidance (A–D) and optokinetic testing (E) in an independent cohort. A–E, Active avoidance (A–D) and optokinetic testing (E) in an independent.

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Invest. Ophthalmol. Vis. Sci ;53(12): doi: /iovs Figure Legend:

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A–E, Active avoidance (A–D) and optokinetic testing (E) in an independent cohort. A–E, Active avoidance (A–D) and optokinetic testing (E) in an independent cohort. Visual active avoidance is mildly impaired in 19-month-old mice. A, The percentage of successful active avoidance trials is shown in blocks of 20 trials over the 2 day test period for the visual version of the task. B, Slopes of the percentage of avoidance per trial are shown for both AA training days. C, D, The percentages of escapes (C) and escape failures (D) are shown in blocks of 20 trials over the 2 day test period. E, Contrast sensitivity from optokinetic tests is shown across varying spatial frequencies (in c/d). Values are expressed as the mean ± SEM. SEMs are not visible in E since they range from only 0.014 to 0.092 across age groups and spatial frequencies. $p < 0.1, ***p < 0.0001. Martin Weber et al. eneuro 2015;2:ENEURO.0047-15.2015 ©2015 by Society for Neuroscience