Volume 54, Issue 2, Pages 546-553 (August 1998) Clinical application of the Personal Dialysis Capacity (PDC) test: Serial analysis of peritoneal function in CAPD patients  Hirokazu Imai, Ken Satoh, Hiroshi Ohtani, Keiko Hamai, Toshiyuki Haseyama, Atsushi Komatsuda, Akira B. Miura  Kidney International  Volume 54, Issue 2, Pages 546-553 (August 1998) DOI: 10.1046/j.1523-1755.1998.00010.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 (A) Change in the urea generation rate. -0.0281 + 0.1784X - 0.0523X2 + 0.0056X3 - 0.00026X4 (r = 0.368). (B) Change in the creatinine generation rate was: 0.4172X - 0.1312X2 + 0.00711X3 (r = 0.351). (C) The change of PNA/PCR was: 0.6525X - 0.1157X2 + 0.00537X3 (r = 0.320). Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Water balance. (A) Change in the urine volume over time. The urine volume became zero after six years. (B) Peritoneum (PD) removal decreased to below 1000 ml/day after eight years, except in two patients. (C) The change of total ultrafiltration. Note that the pattern is same as in B. Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Creatinine clearance (CCr). (A) The change of residual renal CCr: 0.9281X + 0.1023X2 - 0.00328X3 (r = 0.603). (B) The change of peritoneum (PD) CCr: 0.0316X + 0.0378X2 - 0.00219X3 (r = 0.366). (C) The change of total CCr: Y = 8.1272 - 0.9466X + 0.1390X2 - 0.00604X3 (r = 0.403). Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 (A) The change of weekly urea KT/V. 0.3801X + 0.0682X2 - 0.00352X3 (r = 0.318). (B) The change of protein loss via the peritoneum (PD). 0.2463X - 0.0342X2 + 0.00309X3 (r = 0.346). Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 5 The relationship between weekly urea KT/V and creatinine clearance (CCr). (A) The relationship between weekly urea KT/V and residual renal CCr. 1.9431 + 0.2495X (r = 0.60). (B) The relationship between weekly urea KT/V and PD CCr. -3.8562 + 3.8687X - 0.8056X2 + 0.0544X3 (r = 0.75). (C) The relationship between weekly urea KT/V and total CCr. -0.2798 + 0.3720X (r = 0.915). Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 6 The change of water removal via the peritoneum (PD) in the serial analysis. The water removal via PD decreased in seven patients after more than four years. Their rates varied from -3.04 to -25.39 ml/week, and the mean value ± sd was -10.03 ± 6.59 ml/week. In 6 of 10 patients after less than one year, the rates were between +1.92 and +23.06 ml/week, and the mean value ± sd was +14.41 ± 7.84 ml/week. The decreased water removal via PD in four patients were caused by lupus nephritis, renal amyloidosis, IgA nephropathy, and an unknown cause. Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 546-553DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 546-553DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 546-553DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, 546-553DOI: (10.1046/j.1523-1755.1998.00010.x) Copyright © 1998 International Society of Nephrology Terms and Conditions