Volume 55, Issue 3, Pages (March 1999)

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Volume 55, Issue 3, Pages 1072-1080 (March 1999) Effect of MTHFR 677C>T on plasma total homocysteine levels in renal graft recipients  Manuela Födinger, Gabriele Wölfl, Gottfried Fischer, Susanne Rasoul-Rockenschaub, Rainer Schmid, Walter H. Hörl, Gere Sunder- Plassmann  Kidney International  Volume 55, Issue 3, Pages 1072-1080 (March 1999) DOI: 10.1046/j.1523-1755.1999.0550031072.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Nonadjusted mean total homocysteine (□; μmol/liter) and folate (▪; nmol/liter) plasma concentrations in kidney graft recipients matched for sex, age, glomerular filtration rate (GFR), and body mass index with respect to the C677T MTHFR gene polymorphism (63 patients in each genotype group). Whiskers denote ±SD. *P < 0.05 for plasma folate levels of the wild-type (CC) vs. heterozygous (CT) and homozygous mutant (TT) genotype patients; **P < 0.05 for total homocysteine concentrations of TT vs. CT and CC patients. Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Nonadjusted total homocysteine (tHcy) plasma concentrations according to the glomerular filtration rate (GFR) in the three groups of kidney graft recipients with (A) wild-type (CC), (B) heterozygous (CT), and (C) homozygous mutant (TT) MTHFR alleles. Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Mean total homocysteine (tHcy) concentrations in patients with a glomerular filtration rate (GFR)> the whole sample median (▪) and in patients with GFR ≤ the sample median (□) according to the MTHFR C677T gene polymorphism (63 patients in each genotype group). *P < 0.05 for plasma total homocysteine concentrations of TT vs. CT and CC patients with GFR ≤ sample median; **P < 0.05 for plasma total homocysteine concentrations of TT vs. CT and CC patients with a GFR more than sample median. Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 1072-1080DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1072-1080DOI: (10.1046/j.1523-1755.1999.0550031072.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

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