Natural History of Ascending Aortic Aneurysms in the Setting of an Unreplaced Bicuspid Aortic Valve Ryan R. Davies, MD, Ryan K. Kaple, BA, Divakar Mandapati,

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Presentation transcript:

Natural History of Ascending Aortic Aneurysms in the Setting of an Unreplaced Bicuspid Aortic Valve Ryan R. Davies, MD, Ryan K. Kaple, BA, Divakar Mandapati, MD, Amy Gallo, MD, Donald M. Botta, MD, John A. Elefteriades, MD, Michael A. Coady, MD, MPH The Annals of Thoracic Surgery Volume 83, Issue 4, Pages 1338-1344 (April 2007) DOI: 10.1016/j.athoracsur.2006.10.074 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier cumulative survival before operative repair. Five-year survival rate before operative repair is given as a function of valve type. Bicuspid aortic valves (BAV [group A; black line]) are associated with a lower preoperative mortality rate (p = 0.0006). (Gray line = group B, all others; error bars = standard error of the survival estimate; p = 0.0001.) The Annals of Thoracic Surgery 2007 83, 1338-1344DOI: (10.1016/j.athoracsur.2006.10.074) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier cumulative survival. Five-year survival is given as a function of valve type. Bicuspid aortic valves (BAV [group A, black line]) are associated with a lower mortality rate (p = 0.0001). (Gray line = group B, all others; error bars = standard error of the survival estimate; p < 0.0001.) The Annals of Thoracic Surgery 2007 83, 1338-1344DOI: (10.1016/j.athoracsur.2006.10.074) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Freedom from negative event (dissection, rupture, or death) for patients in group B (all others). Five-year event-free survival is given as a function of valve stenosis. (Black line = stenotic valve; gray line = nonstenotic valve; error bars = standard error of the freedom from negative events; p = 0.7319.) The Annals of Thoracic Surgery 2007 83, 1338-1344DOI: (10.1016/j.athoracsur.2006.10.074) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Freedom from negative event (dissection, rupture, or death) in patients in group A (bicuspid aortic valves). Five-year event-free survival is given as a function of valve stenosis. (Black line = stenotic valve; gray line = nonstenotic valve; error bars = standard error of the freedom from negative events; p = 0.0096.) The Annals of Thoracic Surgery 2007 83, 1338-1344DOI: (10.1016/j.athoracsur.2006.10.074) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions