Discrepancy between frequency domain optical coherence tomography and intravascular ultrasound in human coronary arteries and in a phantom in vitro coronary.

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Discrepancy between frequency domain optical coherence tomography and intravascular ultrasound in human coronary arteries and in a phantom in vitro coronary model In-Cheol Kim, Chang-Wook Nam, Yun-Kyeong Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, In-Sung Chung, Seongwook Han, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim International Journal of Cardiology Volume 221, Pages 860-866 (October 2016) DOI: 10.1016/j.ijcard.2016.07.080 Copyright © 2016 The Authors Terms and Conditions

Fig. 1 Representative images of FD-OCT and IVUS at the same segment of phantom reference (A and B), phantom stent (C and D), human coronary artery (E and F), and human coronary artery with stent (G and H). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions

Fig. 2 Comparisons of diameter and area among actual phantom size (light blue), and FD-OCT (red) and IVUS (dark blue) measurements at the non-stented reference site (A) and stented segment (B) of phantom coronary model. (*, p<0.001; FD-OCT, frequency domain optical coherence tomography; IVUS, intravascular ultrasound). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions

Fig. 3 Comparisons of diameter (A) and area (B) among FD-OCT (red), IVUS (dark blue) and QCA (green) measurements at the non-stented reference site and stented segment of human coronary artery. (QCA, quantitative coronary angiography; FD-OCT, frequency domain optical coherence tomography; IVUS, intravascular ultrasound; *, p<0.05; **, p<0.001). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions

Fig. 4 Bland–Altman plots of differences between reference (left) and stent (right) diameter (upper panel) and area (lower panel) between IVUS and FD-OCT. (IVUS, intravascular ultrasound; OCT, optical coherence tomography). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions

Fig. 5 Correlation between IVUS measured diameter and FD-OCT measured diameter at the reference segment and the stented segment (upper panel). Correlation between IVUS measured area and FD-OCT measured area at the reference segment and the stented segment (lower panel). Note correlation between IVUS and OCT measured diameter and area are greater at the stented segment than at the reference segment. (IVUS, intravascular ultrasound; OCT, optical coherence tomography). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions

Fig. 6 Relative difference in percentage of mechanism contribution to difference between IVUS and FD-OCT measurements in previous studies and the present study. (LA, lumen area; SA, stent area; MLA, minimum lumen area; Relative difference percentage (%)=100×(IVUS measurement−OCT measurement)/IVUS measurement). International Journal of Cardiology 2016 221, 860-866DOI: (10.1016/j.ijcard.2016.07.080) Copyright © 2016 The Authors Terms and Conditions