Influence of medial meniscectomy on stress distribution of the femoral cartilage in porcine knees: a 3D reconstructed T2 mapping study T. Shiomi, T.

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Influence of medial meniscectomy on stress distribution of the femoral cartilage in porcine knees: a 3D reconstructed T2 mapping study T. Shiomi, T. Nishii, S. Tamura, H. Tanaka, K. Murase, H. Yoshikawa, N. Sugano Osteoarthritis and Cartilage Volume 20, Issue 11, Pages 1383-1390 (November 2012) DOI: 10.1016/j.joca.2012.07.015 Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 The custom-made compression device along with a porcine knee joint in the neutral position. Axial compression force was transmitted to the knee joint through a sliding plate (asterisk) bounded by a viscoelastic foam material (black arrow). (A) Neutral position. (B) 10° varus position. Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 (a): Representative 3D anatomical surface model of the femoral cartilage constructed from FIESTA-C images. (b): 3D anatomical surface model of the femoral cartilage with meniscus (c): 2D sagittal femoral cartilage T2 of the lateral condyle. (d): Femoral cartilage T2 maps (right) overlaid on the 3D anatomical surface model of the distal femur with menisci (translucent). Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Definition of ROIs in the femoral cartilage on the basis of the meniscus. On the cartilage of each lateral and medial condyle, six ROIs of equal area based on the medial and lateral menisci (zones in medial condyle; M1: peripheral anterior zone, M2: peripheral intermediate zone, M3: peripheral posterior zone, M4: central anterior zone, M5: central intermediate zone, and M6: central posterior zone, as well as L1–L6 in the lateral condyle). Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Representative 3D reconstructed T2 mapping of femoral cartilage under each condition before meniscectomy. Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 5 Representative 3D reconstructed T2 mapping of femoral cartilage under each condition after meniscectomy. Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 6 The decrease rate in T2 values [with error bars indicating 95% confidence interval (CI)] under Condition L compared with Condition N before and after meniscectomy (N = 10). The changes were calculated as (values under Condition N − values under Condition L)/values at Condition N × 100. (*) Significant difference of the decrease rate in cartilage T2 between Condition N and Condition L. Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 7 The decrease rate in T2 values (with error bars indicating 95% CI) under Condition V compared with Condition N before and after meniscectomy (N = 10). The changes were calculated as (values at Condition N − values at Condition V)/values at Condition N × 100. (*) Significant difference of the decrease rate in cartilage T2 between Condition N and Condition V. Osteoarthritis and Cartilage 2012 20, 1383-1390DOI: (10.1016/j.joca.2012.07.015) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions